Forty‐one patients with benign and malignant neurogenous tumors arising in the head and neck are reviewed. The gross and microscopic characteristics of these tumors are related to their prognosis and treatment. The nerve sheath tumors encountered in this region paralleled those seen elsewhere. Because of the lack of circumscription, total excision of neurofibromas frequently was difficult. Lack of recognition of early changes of malignancy led to initial misdiagnosis of two of the three neurogenous sarcomas. Neoplasms of sympathetic nervous system origin were uncommon; only two neuroblastomas were seen. Possible pitfalls in the histologic interpretation of olfactory neuroblastomas are noted. In several of these patients there was surprising lack of correlation of their clinical course with the histologic appearance of their neoplasm.
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