ObjectiveWe aimed to study the role of magnetic resonance imaging (MRI), including a
novel MRI sequence-the modified volumetric interpolated breath-hold
examination (VIBE)-in the characterization of the fetal skeleton. This novel
sequence was useful for reconstructing three-dimensional images of the
skeleton.Materials and MethodsWe enrolled 22 pregnant women whose fetuses had shown congenital
abnormalities on ultrasound examinations. The women underwent prenatal fetal
MRI in a 1.5-T scanner with a T2-weighted modified VIBE sequence.
Three-dimensional reconstructions of the fetal skeleton were performed
manually on the instrument itself or via an interactive pen-tablet
workstation.ResultsThree-dimensional reconstructions of the fetal skeleton were performed after
the acquisition of modified VIBE MRI sequences, and it was possible to
characterize the fetal skeleton in all MRI examinations.ConclusionA detailed evaluation of the three-dimensional reconstructions of fetal
skeleton performed after acquisition of a modified VIBE MRI sequence allowed
a full characterization of the skeleton. However, improvements to the
proposed sequence should be addressed in future studies.
Objective To assess the applicability of magnetic resonance imaging (MRI) to complement ultrasound in the diagnosis of fetal urinary tract anomalies. Methods This was a retrospective cohort study that included 41 women between 19 weeks and 37 weeks and 6 days of gestation carrying fetuses with malformations of the urinary tract which were initially diagnosed by ultrasound and then referred for MRI. In all cases, the diagnosis was confirmed after birth either through imaging or autopsy. A surface coil was positioned over the abdomen and T2-weighted sequences were obtained in the axial, coronal, and sagittal planes; T1 in at least one plane; and three-dimensional (3-D) TRUFI in fetuses with dilatation of the urinary tract. Results Mean gestational age at the time of MRI examination was 28.21 weeks. The rapid T2 sequences allowed all the anomalies of the fetal urinary tract to be assessed, whereas 3-D TRUFI sequencing proved very useful in evaluating anomalies involving dilatation of the urinary tract. The signs of pulmonary hypoplasia characterized by hypointense signal in the T2-weighted sequences were identified in 13 of the 41 fetuses. Conclusion MRI confirmed and added information to the ultrasound regarding fetal urinary tract anomalies, as well as information related to the other associated malformations, their progress in the prenatal period, and possible postnatal prognosis.
In this study, children were at significantly higher odds of being treated for trauma while on a highway with heavy traffic flow. The most common sites of injury in this sample were the lower extremities and the head, face, and neck complex.
Hypoglycemia is the most frequent metabolic abnormality in the newborn, but no consensus exists on what level of blood glucose is able to protect the brain and influence the child's neural development and which is the best course of management in cases labeled as hypoglycemia. Early diagnosis, urgent treatment, and prevention of future episodes of hypoglycemia are the cornerstones of management, now supported by recent advances in molecular genetics and in our understanding of the pathophysiology of neonatal hypoglycemia, particularly the pathogenesis of congenital hyperinsulinemic hypoglycemia.
Introdução: o peixe foi e sempre será uma importante fonte de proteína na alimentação. Objetivo: verificar se a quantidade de peixe ingerida durante uma gravidez normal pode influenciar na idade gestacional e peso ao nascimento. Métodos: estudo-piloto retrospectivo com análise de dados gerados e armazenados em banco de dados após aplicação de questionário estruturado e avaliação de prontuários de puérperas e seus recém-nascidos. Foram recolhidos elementos relacionados à gestação, ao recém-nascido e informações referentes à ingestão de peixes e frutos do mar. Após a aplicação dos critérios de exclusão, foi testada a relação entre variáveis categóricas com o teste de qui-quadrado e Kruskal-Wallis para as variáveis contínuas, todos com significância de 0,05. Resultados: entre 309 binômios mãe-filho 40 foram selecionados, sendo que a maioria morava em Niterói (38/40). A média de idade foi de 24,8 anos e o número médio de consultas de pré-natal foi de 5,7. Nenhum recém-nascido precisou de reanimação e a média da idade gestacional e do peso ao nascimento foram, respectivamente, 39,2 semanas e 3.224,2 gramas. A maioria ingeriu pescados esporadicamente (n = 11; 32,5%). Sete (17,5%) declararam ingerir peixe duas vezes ou mais por semana. A idade gestacional de nascimento foi significativamente diferente (p = 0,012) quando comparadas às mães que referiram baixa e alta ingestão de peixe. Conclusões: a maioria das mulheres analisadas não ingeriu a quantidade recomendada de peixe durante a gravidez. O consumo de peixe não influenciou significativamente no peso neonatal, entretanto a idade gestacional de nascimento foi menor no grupo que referiu maior ingesta de pescados.
Characterize and investigate determinants of seasonality in hospitalization of patients with Bipolar Disorder (BD).Data was obtained from all 111 psychiatry admissions of patients with BD as the primary diagnose in Barreiro-Montijo Hospital Center, located in Lisbon Metropolitan Area, in 2017. Data was analysed with SPSS® version 22. Association between admission's season, sex and BD polarity was investigated with chi-square test and association between admission's season and age was investigated with ANOVA test. The associations were considered significant if p value <0,05.
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