STEATORRHOEA unsteadiness when she walked. On examination she was pale but fairly well nourished; her tongue was smooth, the lower abdomen was distended, and there was oedema of the ankles. The blood pressure was 100/60 and there were signs of a sensory peripheral neuritis.A four-day fat balance showed 78% absorption; the haemoglobin was 8.2 g. per 100 ml.; M.C.V., 133 cubic microns; M.C.H.C., 33%. The bone marrow was partly normoblastic and partly megaloblastic. A fractional test meal showed a histamine-fast achlorhydria, and a glucosetolerance test was normal. A barium-meal examination showed distension of the small bowel with delay in transit. An injection of 1,000 pg. of vitamin B12 raised the haemoglobin to 10.9 g. per 100 ml. She was then given chlortetracycline, 250 mg. four-hourly for ten days; the diarrhoea diminished, and the reticulocyte count rose from 10/% to 12%
From the Obstetrical Unit and BioChemical Laboratory of the Royal Frce Hospital, lUniversity of London. PART I.-CLINICAL INVESTIGATION. DIABETES was looked upon as a very serious disease in the few cases where it was coinplicated by pregnancy. Since the discovery of insulin as a means of treatment the whole aspect of the condition has changed. Our views have, therefore, to be modified as to the dangers of pregnancy in this disease. The older literature gives records of a comparatively small number of cases of diabetes Read at the Obstetrical Section of the Royal Society of Medicine, June 19, 1931. due to the inhlibitive influence of the disease upon the function of reproduction. Ovulation ceases and atrophic changes take place copyright.
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