Fluoride toothpaste is one of the most effective cariostatic product when used as a daily fluoride application. The purpose of this in vitro study was to evaluate the effect of a new fluoride-containing toothpaste on enamel surface microhardness (SMH) under a pH-cycling regimen. Methods: Thirty-five sound human enamel samples were randomly divided into five groups (A-E) each containing seven samples as A (fluoridefree control group), B (1000 ppm NaF), C [KNO 3 (5%), 1450 ppm NaF], D (1450 ppm sodium monofluorophosphate), and E (1450 ppm NaF). After inducing caries-like lesions, each group was maintained daily for de-and remineralization cycle for seven days. During this cycle, samples were treated by the selected toothpaste for each group. Enamel mineral loss was assessed by SMH and lesion depth was analyzed by polarized light microscopy (PLM). Surface enamel microhardness was determined on the enamel blocks. SMH recovery (%SMHR) among treatments was analyzed by a two-way ANOVA. Results: The highest values of %SMHR were observed for the 1450 ppm NaF (group C). NaF toothpastes significantly increased the microhardness of the lesions (p<0.001) when compared to control groups. PLM data revealed a mineral precipitation band on the surface layer of all samples but no difference was found between groups in terms of enamel remineralization layers (p>0.05). The results suggest that all toothpastes with similar sources/concentrations of fluoride, provide different levels of remineralization. Conclusion: It can be concluded that new NaF compounds in toothpaste result in a clearly marked remineralization of caries-like enamel lesions.
Background: In recent literatures, much attention has been given to natural products for their health benefits. Aims: In this study, the objective was to measure the efficacy of the ginger-honey-chocolate mixture as the remineralization effect has been shown in the literature previously and to evaluate the individual contributions of this mixture; ginger, natural honey, bitter chocolate separately on remineralization of initial enamel caries lesion. Materials and Methods: All specimens were divided into eight groups as: Ginger (Arifoglu®, Turkey) in powder form, (n = 8); Ginger-Honey-Chocolate (n = 8); Natural honey (Balparmak Plateau Blossom Honey®, Turkey) (n = 9); Bitter chocolate (Nestlé®, Switzerland) (n = 8); MI Paste (GC, Japan) (n = 8); Paradontax (Sensodyne, Glaxosmithklein, USA) (n = 9); Pronamel (Sensodyne, Glaxosmithklein, USA) (n = 9); Control (n = 9) groups. Samples were carried out five pH cycles along 7 days at 37°C for each group. During pH cycling, blocks were put in a demineralization (6 h) and a remineralization solution (18 h). The treatment consisted of 1 min. interaction of enamel surfaces with agent/deionized slurries (1:3 w/w) on a daily basis. The surface microhardness (SMH) was determined before and after pH cycling with a Digital Micro-Vickers Hardness Tester (Wilson Wolpert; Europe BV, 401 MVD, Netherlands). Mineral changes were determined by using FluoreCam® and recovery values were calculated as SMHR% and FΔ%, respectively. Results: All groups showed an enhanced remineralization. There was no significant difference in terms of FΔ% (F = 1.223, P = 0.304) and SMHR% (F = 0.709, P = 0.664) between all groups. Conclusion: The herbals (ginger, honey, and bitter chocolate) examined in this study gave promising results with a high remineralization potential.
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