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Background Over half of the children living with HIV/AIDS suffer from severe acute malnutrition especially in countries having food insecurity like Ethiopia. However, determinants of severe acute malnutrition among HIV-positive children receiving care and treatment in antiretroviral therapy clinics in Ethiopia are not abundantly investigated. The aim of this study was to assess the determinants of severe acute malnutrition among HIV-positive children receiving highly active antiretroviral therapy in public health institutions of the North Wollo Zone, Northeastern Ethiopia. Methods An institutional-based unmatched case–control study was conducted on 204 under-fifteen, HIV-positive children (68 cases and 136 controls). The data were collected by reviewing medical records and by interviewing attendants. Binary and multiple logistic regressions were employed, and odds ratio with 95%CI was used to interpret results. A p -value of <0.05 was considered as a significant difference between cases and controls for the exposure variable of interest. Results A total of 204 under-fifteen, HIV-positive children were included in this study. Of them, 49.5% were males. About 79.4% of those children had acquired HIV infection through vertical transmission. Poor adherence to ART Adj-OR: 5.72 (1.08–30.27), duration on ART Adj-OR: 5.54 (1.44–21.24), severe immunodeficiency Adj-OR: 6.41 (1.09–37.86), advanced WHO clinical stage Adj-OR: 3.58 (1.03–12.43), oropharyngeal disease Adj-OR: 4.72 (1.13–19.73) and chronic diarrhea Adj-OR: 3.98 (1.05–15.04) were identified to be determinants of SAM in those children. Conclusion Determinant factors for SAM among HIV-positive children were chronic diarrhea, severe immunodeficiency, duration and adherence to ART, oropharyngeal disease and advanced WHO clinical stage. Therefore, it is better if interventions are developed and implemented to address these identified factors.

Voluntary counseling and testing (VCT) for HIV is essential and critical way for prevention, care and treatment of HIV. It allows early detection of illness, reducing transmission, morbidity and mortality from it. But youth knowledge and attitude towards HIV testing services is not universal. The aim of this study was to assess knowledge, attitude, practice and factors associated with VCT for HIV among University Students in Ethiopia. Institution based cross sectional study was conducted among University students in Ethiopia using pretested, structured self-administered questionnaire. Single proportion formula was used to calculate the sample size (361). Multistage sampling with stratified sampling technique was used. Data was analyzed using SPSS version 16.0 with chi square test, bivariate and multivariate analysis via OR, AOR, p-value and confidence interval. Binary logistic regression was used. Out of 361 sample 93.6% of them responded, with 178 (52.7%) male and most are below 25 years. Majority were single, orthodox in religion, and from urban residence. 86% of them have heard of voluntary testing for HIV and know that having early test will prevent future spread of HIV. Based on the scoring 66% are knowledgeable about VCT. Almost 60% of participants were willing to undergo the test and 80% advices their friends to have test. Also 40.5% had good attitude toward test for HIV and 65.7 and 29.6% were ever tested and tested in the previous year respectively. Fear of HIV test results, stigma, and service related factors were major barriers for testing. Being male (AOR=1.607, CI: (1.01-2.57) p value= 0.047) and first year (AOR= 3.25, 1.33 -8.83) were significantly had lower odds of being knowledgeable than females and seniors respectively. Those who were not knowledgeable have two times odd of poor attitude (AOR=1.901(1.20-3.02) P=0.006)). Students from urban (AOR=2.088, CI: (1.273-3.425) P=0.004), unseparated family (AOR=2.24CI: (1.02-4.92) P=0.045) and with poor attitude (AOR= 1.76 CI: (1.08-2.89) p=0.024) were more likely not to have test than counterparts. Knowledge and attitude towards HIV testing is not satisfactory. Freshman students are the target for behavioral interventions. Improving awareness and attitude of students through peer to peer discussion and other packages is crucial to increase the practice and ultimately combat HIV in higher institutions.

Introduction Perinatal asphyxia continues to be a significant clinical concern around the world as the consequences can be devastating. World Health Organization data indicates perinatal asphyxia is encountered amongst 6–10 newborns per 1000 live full-term birth, and the figures are higher for low and middle-income countries. Nevertheless, studies on the prevalence of asphyxia and the extent of the problem in poorly resourced southern Ethiopian regions are limited. This study aimed to determine the magnitude of perinatal asphyxia and its associated factors. Methods A retrospective cross-sectional study design was used from March to April 2020. Data was collected from charts of neonates who were admitted to NICU from January 2016 to December 31, 2019. Result The review of 311 neonates’ medical records revealed that 41.2% of the neonates experienced perinatal asphyxia. Preeclampsia during pregnancy (AOR = 6.2, 95%CI:3.1–12.3), antepartum hemorrhage (AOR = 4.5, 95%CI:2.3–8.6), gestational diabetes mellitus (AOR = 4.2, 95%CI:1.9–9.2), premature rupture of membrane (AOR = 2.5, 95%CI:1.33–4.7) fetal distress (AOR = 3,95%CI:1.3–7.0) and meconium-stained amniotic fluid (AOR = 7.7, 95%CI: 3.1–19.3) were the associated factors. Conclusion Substantial percentages of neonates encounter perinatal asphyxia, causing significant morbidity and mortality. Focus on early identification and timely treatment of perinatal asphyxia in hospitals should, therefore, be given priority.

Background: Nurses are exposed to professional burnout due to their exposure to physical, mental, and emotional stressors, which can lead to numerous complications in their personal, social, and organizational life. Objectives: To assess the magnitude of nurses' burnout and its associated factors in public hospitals of Amhara regional state, Ethiopia. Methodology: Institutional based cross-sectional study design was conducted on 369 nurses selected by systematic sampling technique. A structured self-administered Amharic version questionnaire was used. Data was, coded and entered in Epi data version 3.7 and analysed by SPSS version 22 software. Descriptive statistics was used to describe the variables. Multivariate analysis, AOR, 95%CI and p-value<0.05 were used to identify variables which had significant association with dependant variable. Permission was obtained from Institution Review Board (IRB) of Addis Ababa University. Information obtained from participants was kept secured and confidential. Result: A total of 369 participant nurses were included in this study, with response rate of 100%, from these respondents 186 nurses (50.4%) were suffered from professional burnout. There is significant association between burnout and educational status [AOR=3.

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Point your SmartPhone at the code above. If you have a QR code reader the video abstract will appear. Or use: https://youtu.be/UnTGt1PwdA4 Objective: Globally, nearly 38 million people are living with HIV, and 1.8 million are children. Each day approximately 5600 people acquire HIV. Since the emerging of HIV, 78 million people have been infected and close to 39 million have died. In developing countries, from all new HIV infections, half are because of mother-to-child transmission (MTCT). The aim of this study is to evaluate the effect of option B+ prevention of mother-to-child HIV transmission (PMTCT) and to develop strategies that contribute to eliminate MTCT in Addis Ababa, Ethiopia. Methods: The study was conducted in three hospitals of Addis Ababa, Ethiopia, with a qualitative approach. Sixteen (16) in-depth interviews of HIV-positive mothers who had PMTCT follow-up and six focus group discussions with health professionals who work at a PMTCT unit were conducted. To analyse the data ATLAS.ti version 7 was used. Results: According to the findings of this study mother-to-child HIV transmission was associated with lack of HIV-discordant couples counselling guideline, lack of HIV disclosure strategy and counselling guidelines, unavailability of special PMTCT counselling guideline for HIV-positive commercial sex worker mothers and lack of HIV-free human breast milk (banked human breast milk) for PMTCT. Based on the study findings, a strategy that contributes to eliminate MTCT was developed. Conclusion: Based on the research finding, the following four strategies were developed. Strategy 1: establish and use banked human breast milk for elimination of MTCT; Strategy 2: incorporate obligatory policy for discordant couple testing, counselling and disclosure with option B+ PMTCT; Strategy 3: develop disclosure policy and counselling guideline for PMTCT; and Strategy 4: formulate special PMTCT guideline for HIV-positive commercial sex worker mothers.

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