Erythroxylum suberosum (Erythroxylaceae) is used in traditional Brazilian medicine as antidiarrheal, astringent, antirheumatic, anesthetic and against indigestion. The objectives of this study were to perform classical phytochemical screening, determine the total phenolic content and the antioxidant activity of ethanol and ethyl acetate extracts of E. suberosum. The extracts of the leaves were obtained by maceration. Phytochemical screening was performed using Thin Layer Chromatography (TLC) and specific reactions. Total phenolic content was determined using the Folin-Ciocalteu method. The antioxidant activity of the extracts was performed by reduction of DPPH, reduction of Fe +3 and Cyclic Voltammetry (CV). Phytochemical screening suggested the presence of alkaloids, coumarins, flavonoids, anthocyanins and condensed tannins in ethanol extract and flavonoids and triterpenes/steroids in the ethyl acetate extract. The amount of total phenolics detected was expressive, especially in the ethanol extract (575.50±2.50 mg gG 1 of ethanol extract and 242.20±9.53 mg gG 1 of extract in ethyl acetate). The ethanol extract showed higher antioxidant activity in the three methodologies employed (DPPH: IC 50 of 0.18 mg mLG 1 , reduction of metal ion at 0.3 mg mLG 1 : 0.903±0.006-absorbance at 700 nm, CV: Increase of anodic current at 1.0 V at 2 mg extract mLG 1) in comparison with the extract in ethyl acetate (DPPH: IC 50 of 0.74 mg mLG 1 , reduction of metal ion at 0.3 mg mLG 1 : 0.871±0.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.