Background: To evaluate oral conditions, demographic and socioeconomic characteristics of oral health-related quality of life in adolescents. Methods: umbrella review, conducted according to the PRISMA checklist. The search strategy used a combination of words, applied in the electronic databases PubMed, WebScience, Embase, Lilacs, Scopus and Cochrane. Included publications until January 2022, without restrictions. Data collection took place with systematized practices and the eligibility criteria were studies focusing on quality of life related to oral health; teenagers; present the term “systematic review” and/or “meta-analysis” in the title or abstract. The quality assessment used the Assessment of Multiple Systematic Reviews (AMSTAR2) and the adherence of the article to the Preferred Reporting Items for Systematic Reviews and Meta Analyzes (PRISMA) was verified. Results: 361 articles identified. 21 included. Systematic reviews focus on the English language, between 2009 and 2022 they showed heterogeneity in the methodological structuring process and were considered of low or critically low quality. Clinical conditions associated with worsening in quality of life were dental caries, malocclusion, dental trauma, toothache, edentulism, need for orthodontic treatment, irregular brushing and periodontal disease. Socioeconomic factors related to housing, parental education, access to health care, absence of siblings and nuclear family influence HRQoL. Completion of orthodontic treatment, health promotion programs, dental care and safe housing all have a positive impact. Conclusion: Worse oral health status, older age, female sex and worse socioeconomic status were significantly associated with worse HRQoL.Registration :PROSPERO CRD4202129352