Our data demonstrated that there may be improved neurologic outcomes in patients with SCI who undergo early surgical decompression. Maintenance of MAP ⩾85 mm Hg for 5 consecutive days post-SCI was also associated with higher rates of AIS grade improvement at mean 26.7 days without a statistically significance difference at prolonged follow-up although a higher rate of neurological recovery persisted in patients with MAP ⩾85 mm Hg.

A systematic review of the literature was performed to address pertinent clinical questions regarding deep vein thrombosis (DVT) prophylaxis in the setting of acute spinal cord injury (SCI). Deep vein thromboses are a common occurrence following SCI. Administration of low-molecular-weight heparin (LMWH) within 72 h of injury is recommended to minimize the occurrence of DVT. Furthermore, when surgical intervention is required, LMWH should be held the morning of surgery, and resumed within 24 h post-operatively.

Prognostic study, level II.