Objective: Laparoscopic cholecystectomy (LC) has recognized itself as the ‘gold standard’ treatment of gallstone disease, but it can, sometimes, be related with considerable complication leads to mortality and morbidity. Therefore, this study was intended to assess the frequency of many sources of bleeding in patients underwent laparoscopic cholecystectomy. Methodology: This was a cross sectional study conducted in the Department of Surgery, Bhitai Dental and Medical College Hospital by using consecutive sampling technique. The duration of study was about one year from Feb 2021 to Dec 2021. A total of 163 patients of age between 30 to 55 years of both genders of diagnosed cholecystitis with cholelithiasis, disease duration of >6 weeks identified by patient’s history were included in the study. To assess the effect modification, age, gender, duration of disease, and amount of bleeding and operative time were stratified followed by application of chi-square with a p value < 0.05 considered as significant. Results: The study results showed that out of 163 cases of laparoscopic cholecystectomy, 141(87%) were females and 22(13%) were males with their mean age were 38.99±10.96 years. Bleeding in laparoscopic cholecystectomy from gallbladder bed was reported in 128(79%) cases followed by cystic artery in 28(17%) cases. There were78(80.4%) cases reported bleeding from gallbladder bed in < 40 years of age and 50(75.75%) cases reported in >40 years of age although with an insignificant association between them (p=0.477). 109(77.3%) cases reported bleeding from gallbladder bed in female and 19(86.3%) cases reported in males with an insignificant association between them (p=0.336). Conclusion: This study concluded that the most frequent bleeding site was the gallbladder bed followed by cystic artery in laparoscopic cholecystectomy. Furthermore, bleeding from gallbladder bed was common in females and < 40 years of age although there was an insignificant association observed with respect to age and gender.
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