Background & Objectives: Jaundice is a common clinical aspect during infancy which affects term (60%) and preterm (80%) newborns in the first week of life. One of the most common reasons is glucose-6-phosphate dehydrogenase (G6PD) deficiency that might increase the risk of severe hyperbilirubinemia and kernicterus. The aim of this study was to determine prevalence rate of enzyme deficiency in newborns with jaundice in North Khorasan. We also compared clinical and paraclinical values and complications among G6PD-deficient and normal G6PD infants who were admitted in the hospital due to jaundice. Materials and Methods: This analytic descriptive study was performed on files of newborns with jaundice. Information of babies who admitted due to jaundice such as perinatal history, clinical and laboratory findings were collected and recorded. Data was compared between two groups of normal G6PD and G6PD deficient-neonates. Statistical analysis was carried out using SPSS 17 statistical package. Results: Among 754 admitted infants with jaundice, we found 24(3.2%) babies with G6PD deficiency. We did not find any significant differences between two groups for variables like birth weight, weight on admission, total serum bilirubin, hematocrit, coombs, hospitalization period whereas a significant statistical difference for reticulocyte was recorded. We did not find any relation between G6PD deficiency and number of blood exchange performing. Conclusion: G6PD deficiency is a common enzyme defect among newborns with hyperbilirubinemia (3.2%) in North Khorasan, Iran and may cause severe hyperbilirubinemia and kernicterus. There was significant difference between two groups for reticulocyte count. By screening all infants in high prevalence places and on-time treatment we can prevent further complications of G6PD deficiency disorder.
Introduction: Preterm delivery is one of the essential midwifery problems, which causes a large proportion of infant mortality even in advanced societies. Despite advances in pregnancy care, the frequency of preterm delivery has not decreased. This study aimed to determine the relationship between serum calcium, phosphorus, and magnesium level with preterm labor in pregnant women. Methods: In this descriptive-analytic study, 40 mothers with full-term and 40 mothers with preterm labor were enrolled. Serum levels of calcium, phosphorus, and magnesium were compared and compared. Data were analyzed by SPSS 19 software using statistical tests. The significance level was considered 0.05. Results: In the present study, mean (standard deviation) serum calcium, phosphorus, and magnesium levels respectively were 8.65 (0.72), 3.65 (0.57), and 1.89 (0.47). It was reported mmol / l and in mothers with term labor 8.8 (0.55), 3.53 (0.71) and 1.79 (0.17) mmol / lit, respectively. There was no significant difference between the two groups in the salts.
Conclusions:The results of our study showed no difference in serum levels of calcium, phosphorus, and magnesium in the two groups of women with the term and preterm labor. However, further studies with a higher sample size are needed.
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