Gynecol Oncol 2000;79:44–49
The authors retrospectively reviewed the records of 126 patients with ASCUS using the ThinPrep system and subdivided them into ASCUS favor reactive and ASCUS favor HGSIL. The overall prevalence of dysplasia in this group was 15.9% and was higher among patients in the ASCUS favor HGSIL group. The incidence of high‐grade dysplasia among the 63 patients in the ASCUS favor reactive group was 3.2%; the incidence in the ASCUS favor HGSIL group was 12.7%.
Comment: This report appears to confirm that the finding of ASCUS favor HGSIL is associated with a significant risk of high‐grade dysplasia. These findings are true both in conventional smears and in liquid‐based cytology. The authors suggest that patients with ASCUS favor HGSIL should be offered colposcopic examination. (CJD)
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