A new approach has been developed to prepare amino-terminated monolayers on hydrogen-terminated
silicon surfaces. This two-step procedure is the first method that provides direct control over the surface
density of the amino groups. First, a mixed monolayer of a protected ω-amino-1-alkene and a nonfunctional
1-alkene is prepared on a H-terminated Si surface, using either phthalimide or acetamide as NH2-protecting
groups. Subsequent removal of the protective groups generates the covalently attached NH2-terminated
monolayer, as evidenced from water contact angle measurements, IR spectroscopy, and X-ray photoelectron
spectroscopy. Both protecting groups have their own advantages: use of the phthalimide moiety is
synthetically very convenient; the relatively small acetamide moiety can be used to prepare monolayers
with high densities (>50%) of amine groups. The reactivity of the amine groups has been confirmed by
further modification of the monolayers.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.