From the root bark of Joannesia princeps assufulvenal (l), an unusual fulvenic plant constituent with a bis-sesquiterpene skeleton has been isolated. Its structure was elucidated by spectroscopic methods and corroborated by X-ray crystallographic analysis.Joannesia princeps Vell. (Euphorbiaceae) is indigenous to subtropical and coastal regions of Brazil.2 It grows into a large tree even on poor soil and is named "anda assu" by the native people.2 The plant is cultivated in Africa and Asia.3 Its seeds contain an oil that is applied in folk medicine as a strong purgative4 and also has been used for industrial purpose^.^ The stem bark and the leaves are reported t o be fish toxins.6 Preliminary studies revealed extracts of the root bark to exhibit significant antibacterial, antifungal, and cytotoxic activity. Cyperenal and cyperenol have been detected as the major bioactive principle^.^
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ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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