This pilot study shows that it is possible to collect prospective voice quality data. There are both subjective and objective improvements in voice that persist to at least 2 years after radiotherapy. We propose the use of the methods described here to study voice outcomes in a lager cohort of patients treated with both surgery and radiotherapy.
Enhanced radiosensitivity is an uncommon phenomenon attributable to deficient DNA repair after radiotherapy which can be assessed with the γ-H2AX assay. Reports of radiosensitivity after stereotactic radiosurgery (SRS) are uncommon. We describe a case where the clinical, radiological and laboratory findings suggest enhanced radiosensitivity after SRS for an acoustic neuroma.
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