From measurements of the oscillating flux of the cerebrospinal fluid (CSF) in the aqueduct of Sylvius, we elaborate a patient-based methodology for transmantle pressure (TRP) and shear evaluation. High-resolution anatomical magnetic resonance imaging first permits a precise 3-D anatomical digitalized reconstruction of the Sylvius's aqueduct shape. From this, a very fast approximate numerical flow computation, nevertheless consistent with analytical predictions, is developed. Our approach includes the main contributions of inertial effects coming from the pulsatile flow and curvature effects associated with the aqueduct bending. Integrating the pressure along the aqueduct longitudinal centerline enables the total dynamic hydraulic admittances of the aqueduct to be evaluated, which is the pre-eminent contribution to the CSF pressure difference between the lateral ventricles and the subarachnoidal spaces also called the TRP. The application of the method to 20 healthy human patients validates the hypothesis of the proposed approach and provides a first database for normal aqueduct CSF flow. Finally, the implications of our results for modeling and evaluating intracranial cerebral pressure are discussed.
Nonlinear doubly diffusive convection in two-dimensional enclosures driven by lateral temperature and concentration differences is studied using a combination of analytical and numerical techniques. The study is organized around a special case that allows a static equilibrium. The stationary states that bifurcate from this equilibrium are either symmetric or antisymmetric with respect to diagonal reflection. Local bifurcation analysis around the critical aspect ratio at which both modes appear simultaneously is complemented using numerical continuation. Perturbation of this situation to one in which no static equilibrium exists provides important information about the multiplicity of steady states in this system.
We present a numerical and analytical study of diffusive convection in a rectangular saturated porous cell heated from below and subjected to high frequency vibration. The configuration of the Horton-Rogers-Lapwood problem is adopted. The classical Darcy model is shown to be insufficient to describe the vibrational flow correctly. The relevant system is described by time-averaged Darcy-Boussinesq equations. These equations possess a pure diffusive steady equilibrium solution provided the vibrations are vertical. This solution is linearly stable up to a critical value of the stability parameter depending on the strength of the vibration. The solutions in the neighborhood of the bifurcation point are described analytically as a function of the strength of vibration, and the larger amplitude states are computed numerically using a spectral collocation method. Increasing the vibration amplitude delays the onset of convection and may even create subcritical solutions. The majority of primary bifurcations are of a special type of symmetry-breaking bifurcation even if the system is subjected to vertical vibration.
The generation of two-dimensional thermal convection induced simultaneously by gravity and high-frequency vibration in a bounded rectangular enclosure or in a layer is investigated theoretically and numerically. The horizontal walls of the container are maintained at constant temperatures while the vertical boundaries are thermally insulated, impermeable and adiabatic. General equations for the description of the time-averaged convective flow and, within this framework, the generalized Boussinesq approximation are formulated. These equations are solved using a spectral collocation method to study the influence of vibrations (angle and intensity). Hence, a theoretical study shows that mechanical quasi-equilibrium (i.e., state in which the averaged velocity is zero but the oscillatory component is in general non-zero) is impossible when the direction of vibration is not parallel to the temperature gradient. In the other case, it is proved that the mechanical equilibrium is linearly stable up to a critical value of the unique stability parameter, which depends on the vibrational field. In this paper, it is shown that high-frequency vertical oscillations can delay convective instabilities and, in this way, reduce the convective flow. The isotherms are oriented perpendicular to the axis of vibration. In the case where the direction of vibration is perpendicular to the temperature gradient, small values of the Grashof number, the stability parameter, induce the generation of an average convective flow. When the aspect ratio is large enough, the character of the bifurcation is practically the same as in the limiting case of an infinitely long layer.
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