This review, registered in PROSPERO (CRD42018102582), assessed the effect of temporary anchorage device placement on endodontic complications. A search strategy was followed to identify studies where any temporary anchorage devices contacted or were in proximity to tooth roots in humans. Studies with low possibility of bias and published in English or Latin-character languages were considered for inclusion. Ten studies were identified; five case reports, one clinical study and four studies with intentional injury, totalling 736 temporary anchorage devices in 327 patients. Complications may ensue following temporary anchorage device placement, whether or not root contact occurs. Chronic apical periodontitis developed when there was root injury involving the pulp; necrosis can also occur. When damage was limited to the periodontal ligament, cementum or dentine, repair occurred, normally within 12 weeks. Clinicians should be aware of the potential for endodontic complications during temporary anchorage device placement, as well as during orthodontic treatment.
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