The sections in this article are The Study of Viscoelastic Properties of Polymers by Infrared Spectrometry Dynamic Infrared Linear Dichroism Measured with a Monochromator DIRLD Spectroscopy with a Step‐Scan F ourier Transform Spectrometer Magnitude and Phase Spectra and Two‐Dimensional Correlation Maps Magnitude and Phase Spectra Two‐Dimensional (2‐ D ) Correlation Maps Some Recent Reports of DIRLD DIRLD Spectroscopy with a FT ‐ IR Spectrometer and Digital Signal Processing Summary Appendix: The Photoelastic Modulator

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This review on infrared spectroscopy highlights three areas in which infrared spectroscopy has become increasingly important during the last two years. These areas are two-dimensional infrared (2D IR) spectroscopy, combinatorial chemistry, and human health. This trend is quite evident in the abstracts examined in preparation for this article. No review article is complete without also including some discussion of the current developments in instrumentation. The review is focused on articles published during 1998 and 1999, but occasionally will include articles from earlier work if they provided additional information we thought pertinent. There is a wealth of other very interesting work that has been published and we encourage the reader to pursue them. As the reader follows the article, they should find that each area discussed impacts another area, which shows that the science of infrared spectroscopy is very exciting indeed.

The behaviors of living cells are governed by a series of regulated and confined biochemical reactions. The design and successful construction of synthetic cellular reactors can be useful in a broad range of applications that will bring significant scientific and economic impact. Over the past few decades, DNA self‐assembly has enabled the design and fabrication of sophisticated 1D, 2D, and 3D nanostructures, and is applied to organizing a variety of biomolecular components into prescribed 2D and 3D patterns. In this Concept, the recent and exciting progress in DNA‐scaffolded compartmentalizations and their applications in enzyme encapsulation, lipid membrane assembly, artificial transmembrane nanopores, and smart drug delivery are in focus. Taking advantage of these features promises to deliver breakthroughs toward the attainment of new synthetic and biomimetic reactors.

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