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This paper introduces an on-line particle-filtering (PF)-based framework for fault diagnosis and failure prognosis in non-linear, non-Gaussian systems. This framework considers the implementation of two autonomous modules. A fault detection and identification (FDI) module uses a hybrid state-space model of the plant and a PF algorithm to estimate the state probability density function (pdf) of the system and calculates the probability of a fault condition in realtime. Once the anomalous condition is detected, the available state pdf estimates are used as initial conditions in prognostic routines. The failure prognostic module, on the other hand, predicts the evolution in time of the fault indicator and computes the pdf of the remaining useful life (RUL) of the faulty subsystem, using a non-linear state-space model (with unknown time-varying parameters) and a PF algorithm that updates the current state estimate. The outcome of the prognosis module provides information about the precision and accuracy of long-term predictions, RUL expectations and 95% confidence intervals for the condition under study. Data from a seeded fault test for a UH-60 planetary gear plate are used to validate the proposed approach.

The fractal dimension of a waveform represents a powerful tool for transient detection. In particular, in analysis of electroencephalograms and electrocardiograms, this feature has been used to identify and distinguish specific states of physiologic function. A variety of algorithms are available for the computation of fractal dimension. In this study, the most common methods of estimating the fractal dimension of biomedical signals directly in the time domain (considering the time series as a geometric object) are analyzed and compared. The analysis is performed over both synthetic data and intracranial electroencephalogram data recorded during presurgical evaluation of individuals with epileptic seizures. The advantages and drawbacks of each technique are highlighted. The effects of window size, number of overlapping points, and signal-to-noise ratio are evaluated for each method. This study demonstrates that a careful selection of fractal dimension algorithm is required for specific applications.

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Mechanisms underlying seizure generation are traditionally thought to act over seconds to minutes before clinical seizure onset. We analyzed continuous 3- to 14-day intracranial EEG recordings from five patients with mesial temporal lobe epilepsy obtained during evaluation for epilepsy surgery. We found localized quantitative EEG changes identifying prolonged bursts of complex epileptiform discharges that became more prevalent 7 hr before seizures and highly localized subclinical seizure-like activity that became more frequent 2 hr prior to seizure onset. Accumulated energy increased in the 50 min before seizure onset, compared to baseline. These observations, from a small number of patients, suggest that epileptic seizures may begin as a cascade of electrophysiological events that evolve over hours and that quantitative measures of preseizure electrical activity could possibly be used to predict seizures far in advance of clinical onset.