Aim The value of Kampo medicine for the treatment of pneumonia is unclear. The aim of our study is to investigate the usefulness of shosaikoto for pneumonia in combination with antibiotics. Methods We retrospectively compared 39 cases treated only with Western medicine, including antibiotics (conventional group), with 22 cases treated with Western medicine, including antibiotics, and shosaikoto (combination group). We evaluated the duration of antibiotic treatment after admission, the febrile period, and the duration of oxygen treatment. Results The duration of antibiotic treatment was significantly shorter in the combination group (7 ± 2.25 days) than in the conventional group (8.46 ± 2.28 days; P < 0.05), and the febrile period was also significantly shorter in the combination group (2.95 ± 0.92 days) than in the conventional group (4.09 ± 2.08 days; P < 0.05). The duration of oxygen treatment was not shorter in the combination group (3.85 ± 1.77 days) than in the conventional group (4.11 ± 2.25 days; P = 0.951). Conclusion This study suggests that combination therapy with shosaikoto and antibiotics is useful for bacterial pneumonia.
Case Reactive hypoglycemia can occur due to postprandial insulin hypersecretion. However, no Kampo medicine is known to cause this effect. Herein, we describe a case of reactive hypoglycemia that occurred postprandially as an effect of Kampo medicine. A 42‐year‐old woman was admitted because of chest pain. We prescribed saikokaryukotsuboreito, following which the patient's symptoms improved. However, after 9 months, she experienced persistent fatigue after developing a cold. Therefore, we changed the prescription to hochuekkito and keishikaryukotsuboreito. Nevertheless, discomfort in the epigastric region and back pain developed within a few hours after administration of these medications. Outcome Results of 75 g oral glucose tolerance test (OGTT) showed excessive insulin secretion, potentially as a result of changing Kampo administration. Therefore, the treatment was changed back to saikokaryukotsuboreito, which resolved the postprandial symptoms. Moreover, the insulin hypersecretion disappeared on subsequent 75 g OGTT. Conclusion The promotion of gastric peristaltic function as an effect of Kampo may cause reactive hypoglycemia.
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