In the pursuit of new pharmaceuticals and agrochemicals, chemists in the life science industry require access to mild and robust synthetic methodologies to systematically modify chemical structures, explore novel chemical space, and enable efficient synthesis. In this context, photocatalysis has emerged as a powerful technology for the synthesis of complex and often highly functionalized molecules. This Review aims to summarize the published contributions to the field from the life science industry, including research from industrial-academic partnerships. An overview of the synthetic methodologies developed and strategic applications in chemical synthesis, including peptide functionalization, isotope labeling, and both DNA-encoded and traditional library synthesis, is provided, along with a summary of the state-of-the-art in photoreactor technology and the effective upscaling of photocatalytic reactions.

European Union's Horizon 2020 program Marie Skłodowska-Curie (764920) for funding. We are grateful to the industrial affiliates of the Centre of Excellence for Biocatalysis (CoEBio3) for a studentship to T.M. Scheme 6. AaeUPO-catalyzed hydroxylation of 15 using Au-TiO 2 .Scheme 7. Aryl iodide and sulfinic acid salt cross-coupling model reaction used for reaction optimization.

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The bremsstrahlung x-rays from a laser-solid interaction have been investigated for the use of radiography. The scaling of the x-rays as a function of energy has been characterized and modelled and agrees with previous measurements.