Dipeptidyl peptidase-4 (DPP-4) inhibition is a new treatment for
type-2 diabetes. DPP-4 inhibition increases levels of active GLP-1. GLP-1 enhances
insulin secretion and diminishes glucagon secretion, in this manner reducing glucose
concentrations in blood. A number of DPP-4 inhibitors are under clinical
development. However, the durability and long-term safety of DPP-4 inhibition remain
to be established. These synthetic DPP-4 inhibitors are showing some side effects.
Herbal medicines are alternative medicine over synthetic drugs that can relieve the
patients. Various research studies have been carried all over the world to evaluate
the efficacy of herbs in the treatment of Type II diabetes mellitus. For a long time
type II diabetes mellitus has been treated orally with herbal medicines, because
plant products are frequently prescribed due to their less toxicity than
conventional medicines.
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