This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process. Oxygenated versus standard cold perfusion preservation in kidney transplantation (COMPARE): a randomised, double-blind, paired, phase 3, superiority trial. Authorship Ina Jochmans (PhD), Aukje Brat (Medical degree), Lucy Davies (PhD) 4 , H. Sijbrand Hofker (Medical degree), Fenna E.M. van de Leemkolk (Medical degree), Henri G.
During 12 years of follow-up, there was no survival difference between patients who underwent open or endovascular abdominal aortic aneurysm repair, despite a continuously increasing number of reinterventions in the endovascular repair group. Endograft durability and the need for continued endograft surveillance remain key issues.
The AKA can be localized before surgery in 100% of TAA(A) patients by using MR angiography. Location of the SA-AKA outside the cross-clamped aortic area is attended with stable MEPs. Interestingly, it was found that in most patients in whom the SA-AKA was cross-clamped, MEPs were not affected, thus indicating sufficient collateral blood supply to maintain spinal cord integrity. Nevertheless, preoperative knowledge of SA-AKA location is of importance, because in 32% of patients, spinal cord function was dependent on this supplier. Revascularization of the SA-AKA can thereby reverse spinal cord dysfunction.
In patients with TAAA, most intercostal and lumbar arteries are occluded and spinal cord perfusion depends on an eminent collateral network, which includes lumbar arteries and pelvic circulation. The monitoring of MEPs is a sensitive technique for the assessment of spinal cord ischemia and the identification of segmental arteries that critically contribute to spinal cord perfusion. Surgical strategies on the basis of this technique reduced the incidence rate of neurologic deficit to less than 3%.
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