Timely and effective detection of potential incipient faults in satellites plays an important role in improving their availability and extending their service life. In this paper, the problem of detecting incipient faults using projection vector (PV) and Kullback-Leibler (KL) divergence is studied in the context of detecting incipient faults in satellites. Under the assumption that the variables obey a multidimensional Gaussian distribution and using KL divergence to detect incipient faults, this paper models the optimum PV for detecting incipient faults as an optimization problem. It proves that the PVs obtained by principal component analysis (PCA) are not necessarily the optimum PV for detecting incipient faults. It then compares the on-line probability density function (PDF) with the reference PDF for detecting incipient faults on the local optimum PV. A numerical example and a real satellite fault case were used to assess the validity and superiority of the method proposed in this paper over conventional methods. Since the method takes into account the characteristics of the actual incipient faults, it is more adaptable to various possible incipient faults. Fault detection rates of three simulated faults and the real satellite fault are 98%, 84%, 93% and 92%, respectively.
Detection of faults at the incipient stage is critical to improving the availability and continuity of satellite services. The application of a local optimum projection vector and the Kullback–Leibler (KL) divergence can improve the detection rate of incipient faults. However, this suffers from the problem of high time complexity. We propose decomposing the KL divergence in the original optimization model and applying the property of the generalized Rayleigh quotient to reduce time complexity. Additionally, we establish two distribution models for subfunctions F1(w) and F3(w) to detect the slight anomalous behavior of the mean and covariance. The effectiveness of the proposed method was verified through a numerical simulation case and a real satellite fault case. The results demonstrate the advantages of low computational complexity and high sensitivity to incipient faults.
Timely detection and treatment of possible incipient faults in satellites will effectively reduce the damage and harm they could cause. Although much work has been done concerning fault detection problems, the related questions about satellite incipient faults are little addressed. In this paper, a new satellite incipient fault detection method was proposed by combining the ideas of deviation in unsupervised fault detection methods and classification in supervised fault detection methods. First, the proposed method uses dynamic linear discriminant analysis (LDA) to find an optimal projection vector that separates the in-orbit data from the normal historical data as much as possible. Second, under the assumption that the parameters obey a multidimensional Gaussian distribution, it applies the normal historical data and the optimal projection vector to build a normal model. Finally, it employs the noncentral F-distribution to test whether a fault has occurred. The proposed method was validated using a numerical simulation case and a real satellite fault case. The results show that the method proposed in this paper is more effective at detecting incipient faults than traditional methods.
Cell differentiation results in widespread changes in transcriptional programs as well as multi-level remodeling of three-dimensional genome architecture. Nonetheless, few synthetically investigate the chromatin higher-order landscapes in different T helper (Th) cells. Using RNA-Seq, ATAC-Seq and Hi-C assays, we characterize dynamic changes in chromatin organization at different levels during Naive CD4+ T cells differentiation into T helper 17 (Th17) and T helper 1 (Th1) cells. Upon differentiation, we observe decreased short-range and increased extra-long-range chromatin interactions. Although there is no apparent global switch in the A/B compartments, Th cells display the weaker compartmentalization. A portion of topologically associated domains are rearranged. Furthermore, we identify cell-type specific enhancer-promoter loops, many of which are associated with functional genes in Th cells, such as Rorc facilitating Th17 differentiation and Hif1a responding to intracellular oxygen levels in Th1. Taken together, these results uncover the general patterns of chromatin reorganization and epigenetic landscapes of gene regulation during T helper cell differentiation.
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