Objective: A comprehensive overview of the research output, including conceptual and temporal trends, is required to address the growing AMR burden in Nigeria, which was previously lacking. This study uses bibliometric analysis to show this. Methods: Data from a query of AMR articles in the Dimensions database (PubMed included) were subjected to bibliometric analysis (1972 to 2022). Bibliometric indicators, topic networks were established and topic trends were analyzed by frequency, relevance scores, and trends over time. Results: A total of 0.2% of the papers on AMR published worldwide were written by authors or institutions from Nigeria. In 2021, publications grew by 13.6%. The vast majority of publications (57.18%) were in the field of Medical and Health Sciences, with 2428 papers. The top journal for AMR papers with at least one Nigerian institution affiliation was African Journal of Clinical and Experimental Microbiology, which published 1.8% of these papers. Antimicrobial stewardship, Clinical and laboratory practices on AMR, Public health implications, Traditional and molecular methods, and Phytomedicine and drug discovery were prominent areas of focus for Nigerian researchers. Conclusion: This study provides a comprehensive overview of the AMR research output, highlighting the need of increased research capacity to address the burden of AMR in Nigeria. Because Nigeria is overly reliant on conventional methods of discovery and development, innovation is essential for the future of antibiotics.
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