Objectives: The main purpose of the present study was to determine the efficacy of real-time elastography (RTE) and strain elastography (STE) in the diagnosis of different thyroid diseases. We also aimed to calculate the cut-off points for the differential diagnosis of subacute thyroiditis (SAT), Graves' disease (GD), and Hashimoto's thyroiditis (HT), which have a similar B-mode sonographic appearance. Patients and Methods: A total of 24 patients with GD (10.9%), 94 patients with HT (42.7%), 20 patients with SAT (9.1%), and 82 individuals with normal healthy thyroids (37.3%) were included. Grayscale ultrasound evaluation of thyroid glands was performed with standard transverse and longitudinal planes before sonoelastography. Results:The strain ratios (SRs) (mean ± standard deviation) of patients with GD, HT, and SAT, and the control group (CG) were 14.7 ± 14.8, 8.4 ± 9.6, 23.2 ± 10.8, and 1.37 ± 0.8, respectively. The cut-off points of strain elastography of the patients with GD, HT, and SAT to the CG were 2.69 (sensitivity 92%, specificity 90%, area under the curve (AUC) 0.983; 95% CI), 2.18 (sensitivity 100%, specificity 85%, AUC 0.898), and 5.54 (sensitivity 100%, specificity 100%, AUC 1.000; 95% CI), respectively. The cut-off point of the strain ratios (SR) of the total amount of patients with HT and GD to SAT was 14.79 (sensitivity 80%, specificity 85%, AUC 0.869; 95% CI). Conclusion: Statistically significant differences were noted in the SR values and elasticity scores of the three experimental groups, and the CG. The elasticity scores of the SAT and HT groups were not significantly different from those of the GD group. The diagnostic performance of strain ratio elastography (P < 0.0001) was higher than that of real time elastography (P < 0.001). In terms of differentiating diagnosis, ES could differentiate SAT from HT, but it had no value in differentiating GD from HT and SAT. We also found statistically significant SRs for the differential diagnosis of SAT from GD and HT. Strain elastography could be a useful method for the differential diagnosis of SAT from a healthy population or from other types of thyroiditis such as GD and HT.
The findings of this study suggest that there may be an association between IL-17A (-197 G/A) (rs2275913) polymorphism and non-alcoholic fatty liver disease development in obese Turkish children.
Aim:The role of atherosclerosis in the pathogenesis of ascending thoracic aortic aneurysms is still uncertain. Ultrasonic elastography is a new diagnostic method, the use of which has diversified considerably in recent years. An increase in intima media thickness in the carotid arteries is an early finding of atherosclerosis. Our purpose was to investigate the effect of atherosclerosis in the development of ascending thoracic aortic aneurysms and to be able to recommend a non-invasive and inexpensive scanning method aiming at early diagnosis. Material and Methods: Thirty-three patients with ascending thoracic aortic aneurysms (aTAA group) and 40 patients with normal measurement (control group) values were included in the study. The carotid artery intima media thicknessof carotid arteries were measured using B mode ultrasonography. Elastographic examination of the intima-media was then performed. Results: Body mass index, past smoking status, hypertension, presence of coronary artery disease and hyperlipidemia were higher in the aTAA group than in the control group (p<0.05). No significant difference was determined between these two groups' ultrasonic elastography or intima media thickness in the carotid arteries values (p<0.05). Conclusions: Our findings suggest that the effect of atherosclerosis in the pathogenesis of ascending thoracic aortic aneurysms is limited. Vascular ultrasonic elastography and intima media thickness determination in the carotid arteries appear not to be effective in the evaluation of ascending thoracic aortic aneurysms.
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