Melasma, also called ‘chloasma’, is a common skin condition of adults in which light to dark brown or grayish pigmentation develops, mainly on the face. Although it can affect both genders and any race, it is more common in women. Melasma is an acquired pigmentary disorder described as symmetrical blotchy or splotchy hyperpigmented macules and patches. The aim of this study was to investigate thyroid profile with anti TPO and iron, uric acid level, in male and female patients. It is a cross-sectional observational study done on 76 females and 25 male who were diagnosed with melasma and thyroid profile with anti TPO, serum iron and uric acid levels were measured. In our study females were more affected then males. In females Mean ± SD value of serum TSH (5.1±2.51) and anti-TPO (11.2±3.1) levels were increased when compared to males(4.9±2.54) and (9.2±1.9). Serum iron value was low in females (83.7±30) than males (90±29). All biochemical parameter were not significant but anti TPO and FT3 showed significant (P<0.001) in female with compared to male. Serum uric acid (3.56±0.77) and serum iron (83.7±30) Mean± SD value was low in melasma females than males which is not significant. Females Mean±SD value of T3 (1.30±0.62) and T4(6.8±1.9), FT4 (1.2±0.44) were non significance showed than compared to males and not significant to males T3 (1.33±0.66) and T4(7.1±1.6), FT4 (1.3±0.67) respectively. Melasma is more severe in females than males. Thyroid profile is not the accurate parameter but anti TPO, and iron level are predictive marker of melasma.
Yagya Therapy is an ancient Vedic therapy. Using specific herbs for management of the disease, this novel approach can provide a supportive care in various conditions. Besides, it involves a holistic approach with pulmonary inhalation of herbal vapors through Pranayama. In the thyroid condition, hyper and hypo thyroid, there is imbalance of the T3, T4 and TSH hormones along with complains in associated with quality of life. The present study evaluated thyroid hormonal levels and quality of life in 18 thyroid patient after giving 40 days of Yagya Therapy with application of herbal mixtures for hormonal balance as supportive care. Patients were without any change in the drug and dose in past 6 months. The pre and post evaluation after Yagya Therapy revealed that in just 40 days of Yagya Therapy as supportive care, it helped to achieve the desired pattern in the hyperthyroid patients. In hypothyroid patients (n=9), pattern of increase in the T4 and T3 levels and decrease in TSH level and in the hyperthyroid patients (n=3), decrease in the T4 and T3 level and increase in TSH level were observed (p=0.06). In addition patients reported significant improvement in quality of life in physical weakness (p-value 0.0078), breathing issues (p-value 0.0078), sleep issues (p-value 0.0176), stress (p-value 0.002), indicating the potential of Yagya Therapy in treating and managing Thyroid condition. Yagya Therapy has great potential for management of chronic condition of Thyroid through both balancing thyroid hormones as well as by improving quality of life.
Coronary heart disease is continuously increase in India. Acute myocardial infarction (AMI) and unstable angina are now recognized as part of a spectrum of clinical disease collectively known as acute coronary syndromes (ACS). The serum cholesterol binding reserve, should be a useful factor for predicting the risk of coronary heart disease. Materials and Methods: Subjects who were diagnosed clinically and chemically as CHD patients were selected out of the patients Gandhi Medical College in department of Cardiology, Hamidia Hospital, Bhopal. This study was done in 25 controls and 50 cases which were divided sexwise and age wise. There were 25 controls, 11 females and 14 males. Total coronary arterial diseases cases were 50 in number, There were 14 males & 11 females in acute coronary syndrome cases and were 14 males and 11 females stable angina. Result: The serum cholesterol was higher and SCBR was significantly lower in stable angina (25.7±7mg%) & acute coronary syndrome (60.2±6.2 mg%) as compared to controls (186.1 ±27mg%)and (60.2±6.2 mg%). Lower SCBR the higher tendency to develop atherosclerosis and hence the higher the risk of coronary heart disease. Conclusion: It concluded that SCBR and SC maybe considered together as a better biochemical markers for the risk of atherosclerosis.
Introduction: Chronic Obstructive Pulmonary Disease (COPD) is characterised by persistent airflow limitation and is a global health issue with high social and economic burden. Type 2 Diabetes Mellitus (T2DM) is a major global metabolic disorder affecting approximately 300 million individuals worldwide. Accordingly, chronic low grade systemic inflammation is probably one of the common denominators between COPD and T2DM. Aim: To evaluate the status of systemic inflammation in COPD patient with/without T2DM, using quantitative serum high sensitivity C-Reactive Protein (hs-CRP) and Total Leucocyte Count (TLC). Materials and Methods: This cross-sectional study was conducted for a period of one year from May 2019 to April 2020 on 100 patients of COPD patients attending outpatient department. Either known patients of COPD or patients with complains of chronic cough was evaluated with chest x-ray and pulmonary function test (spirometry) after thorough history and physical examination. Global Initiative for Chronic Obstructive Lung Disease-GOLD guidelines a grading system for COPD was used for assessing severity. For assessing diabetes, criteria adopted from American Diabetes Association (ADA) i.e., symptoms of diabetes plus random plasma glucose >200 mg/dL (11.1 mMol/L). Venous blood samples were obtained to perform quantitative hs-CRP estimation by immune turbidimetry method as a marker of systemic inflammation. Statistical analysis was performed using Statistical Package for the Social Sciences (SPSS) version 26.0 of International Business Machines (IBM) Corporation, California, United States of America (USA). Results: The T2DM was present in 40% COPD patients. The frequencies of T2DM in patients with GOLD stages I, II, III, and IV were 16%, 45%, 28%, and 11%, respectively. The mean hs-CRP levels for diabetic group was 5.45±1.07 mg/L, which was significantly higher (p<0.05) than 2.26±0.69 mg/L that of non diabetic group. Conclusion: Present study concluded that the inflammatory process is a definite pathophysiological factor that has a significant link between COPD and T2DM and can be evaluated using a marker like hs-CRP level and TLC.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.