<p class="Abstract">Anti-snake venom therapy is the only treatment for snake bite but leads to acute and chronic conditions which may be severe. The medicinal plants have gained importance over years to find an effective alternative to anti-snake venom. The present study focused on evaluating the potential of <em>Clerodendrum serratum</em> for the anti-snake venom activity. Phytochemicals were extracted from the <em>C. serratum</em> with different solvents. The ethyl acetate and methanolic extracts were found to neutralize the major enzyme toxins (phospholipase A<sub>2</sub>, protease and hyaluronidase) of <em>Bungarus caeruleus</em> and <em>Daboia russelii</em> venom at a concentration of 100 µg/mL. The fibrinogenolytic activity of both the venoms were neutralized. The study proves that the plant <em>C. serratum</em> possesses certain compounds which inhibit the toxins present in the venom of <em>B. caeruleus</em> and <em>D. russelii</em>.</p><p class="Abstract"><strong>Video Clip of Methodology</strong>:</p><p class="Abstract">Hyaluronidase assay: 3 min 30 sec <a href="https://www.youtube.com/v/Xz5C6bbwgW0">Full Screen</a> <a href="https://www.youtube.com/watch?v=Xz5C6bbwgW0">Alternate</a></p>
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.