McCune-Albright syndrome (MAS) is characterized by a triad of poly/monoostotic fi brous dysplasia, café-au-lait macules and hyperfunctioning endocrinopathies. Association of MAS with GH excess is rare, and in most of the instances somatotropinoma has not been documented. Treatment of patients of MAS with acromegaly is diffi cult because of thickened calvarium and dysplastic skull bone. We report a 17-year-old girl, who presented with cranio-facial fi brous dysplasia, caféau-lait macules and also had acromegaly due to pituitary macroadenoma, and treated with gamma knife radiosurgery.
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