Dihydroxybenzaldehyde-based Schiff base ligands (L 1 -L 3 ) and their ruthenium(II) complexes were synthesized and characterized by elemental analysis, 1 H-, 13 C-and 31 P-NMR, UV-Vis, IR and mass spectroscopy. The DNA binding of the ruthenium(II) complexes was investigated by UV-Vis absorption spectroscopy. The experiments revealed that all the compounds could bind to DNA through electrostatic interactions and the intrinsic binding constants (K b ) were estimated under similar sets of experimental conditions. The absorption spectral study indicated that the ruthenium(II) complexes had intrinsic binding constants in the range of (1.6-8.6)×10 4 mol -1 dm 3 . The complex [Ru(CO)(PPh 3 ) 2 (L 3 )] bound more strongly than the other complexes. In addition, the DNA cleavage properties for all ruthenium(II) complexes were tested.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.