Musical hallucinations are the hearing of tunes, melodies, harmonics, rhythms and timbres. They have been reported to be in association with healing loss in several published cases. The uniqueness of our patient was that she was younger than previously reported cases of musical hallucinations, who were elderly people, and her symptoms of depression disappeared gradually after the initiation of moclobemide.
The rates of psychological distress were higher than expected in a city considered to be safe in terms of earthquake risk. Relocation after the disaster may increase psychological distress by disrupting the social network.
Introduction: Factitious cheilitis is a chronic condition characterized by crusting and ulceration that is probably secondary to chewing and sucking of the lips. Atopy, actinic damage, exfoliative cheilitis, cheilitis granulomatosa or glandularis, contact dermatitis, photosensitivity reactions and neoplasia should be considered in the differential diagnosis of crusted and ulcerated lesions of the lip.
Introduction: There is inconsistent evidence of interaction between childhood adversities and a serotonin transporter promoter polymorphism (5-HTTLPR) in depression. It is hypothesized that genetic sensitivity to stress could be more specific to recurrent major depressive disorder (MDD). The aim of the study is to replicate a recent study which provided preliminary evidence of interaction between severity of childhood maltreatment and the 5-HTTLPR polymorphism in recurrent MDD.Methods: Participants included a well-characterized clinical sample of 70 recurrent MDD cases and 67 never psychiatrically ill controls, aged 18 years or over. Socio-demographic and clinical information form, Composite International Diagnostic Interview (CIDI), Childhood Trauma Questionnaire (CTQ), Beck Depression Inventory (BDI) were applied to both groups, along with genotyping.Results: There was no interaction between childhood maltreatment and the 5-HTTLPR in relation to recurrent MDD. All forms of childhood maltreatment were reported as more severe by cases than controls, and there was an independent association between maltreatment and recurrent MDD.
Conclusion:The path forward to detect genetic risk loci for depression remains challenging. Taking childhood maltreatment history into account could lead to a richer understanding of differences in biological correlates, genetic underpinnings, and outcomes.
Due to the high frequency of living-related donor renal transplantation (LRDRT) in our country, we were concerned both about the recipient and the donor quality of life and psychological well-being. We investigated HRQL and mood in LRDRT recipients, donors, and controls using the Beck Depression Inventory, Beck Anxiety Inventory, and 36-item Short Form Health Survey. The recipient group consisted of 69 individuals who underwent renal transplantation between August 2002 and June 2004. The donor group consisted of 35 and the control group 45 healthy individuals. Multivariate analysis of variance and the post hoc (Tukey) test were used to assess and to analyze differences among and between the three groups. The depression scores of the recipients were higher than donors (P < 0.05) but were similar to controls. The recipient scores indicated poorer physical functioning (P < 0.001), greater physical limitation on roles (P < 0.001), and lower levels of general health (P < 0.01) compared to controls. The donor scores indicated higher vitality (P < 0.01), better social functioning (P < 0.05) and greater mental health (P < 0.01) than controls. Poorer health and mood status among the recipient group might reflect the various negative impacts of chronic debilitating disease. It is therefore recommended to screen recipients regularly for clinically relevant HRQL impairments after transplantation.
Purpose: A homogenous classification cannot be obtained because of Obsessive Compulsive Disorder's (OCD) heterogeneous structure. The present study aimed to determine the relation of gender related differences with clinical features, symptom dimensions, age of onset, comorbidity in OCD patients. As distinct from the other studies we also aimed to evaluate the difference of Yale-Brown Obsessive Compulsive Scale's (Y-BOCS) subscales (insight, avoidance, pathologic doubt and pathologic responsibility, instability, retardation) between male and female patients with OCD. Method: The present study comprised of 198 patients aged between 15 and 65 years, who met the OCD criteria of DSM-IV-TR. Detailed data on clinical and sociodemographic characteristics were recorded. The patients were divided into two groups; male (n=65) and female (n=133). The patients underwent Structured Clinical Interview for DSM-IV Inventory (SCID-I), Yale-Brown Obsessive Compulsive Scale and Check List, Beck Anxiety Inventory, Beck Depression Inventory. Scores of these inventories were statistically compared. Results: There were no statistically significant differences in mean age, marital status, education level, family history, social support, hospitalization and suicidal attempt history between the two groups. We found a high treatment seeking, earlier age onset of obsessive-compulsive (OC) symptoms and disorder in males. We did not find any symptom differences except sexual obsession and repeating compulsion between male and female patients with OCD. We also found high BAI and BDI scores in females. We did not find statistically significant differences in the proportion of comorbid psychiatric disorders and the subscales of Y-BOCS between genders. Conclusion: The present study suggests that age of onset, treatment seeking, anxiety, depression level, and some OC symptoms are different between male and female patients and gender may be used for the classification of the OCD.
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