In this work, we obtained silver nanoparticles stabilized with polyvinylpyrrolidone, ranging in size from 70 to 110 nm, which exhibits good crystallinity and anisotropic structure. For the first time, we studied the influence of the molar ratio of silver between silver and peroxide on the oxidation process of the nanoparticles and determined the regularities of this process by analyzing changes in absorption spectra. Our results showed that at molar ratios of Ag:Н2О2 = 1:1 and 1:5, dependences of changes in the intensity, position and half-width of the absorption band of the plasmon resonance are rectilinear. In vivo studies of silver nanoparticles have shown that silver nanoparticles belong to the toxicity class III (moderately hazardous substance) and to the third group according to the degree of accumulation. We established that silver nanoparticles and oxidized silver nanoparticles form a uniform layer on the surface of the suture material. We found that the use of the suture material with silver nanoparticles and oxidized silver nanoparticles does not cause allergic reactions in the organisms of laboratory animals.

No abstract

In recent decades, there has been an increase in the interest in practical medicine in medicines obtained from raw materials of animal and plant origin -biostimulants and adaptogens. The use of such drugs in strictly dosed amounts can increase the indicators of natural resistance of the body, increase the level of morphological and biochemical parameters of blood, and improve metabolism. In this scientific study, the effect of the combined effects of iodine, amylodextrin, E-selenium, and preparation from the Aloe arborescens Milli extract on the preparation of rams in the seasonal season was studied. The results of the experiment showed that the rams of the experimental group had a faster recovery and preparation of the body for the seasonal season after the winter period precisely due to the use of the non-hormonal stimulation means proposed by us. Our proposed means for stimulating rams in their preparation for the breeding season have a positive effect on the processes of metabolism and spermatogenesis in the body of animals and these drugs can be recommended for use. It has been established that the non-hormonal means used by us to prepare rams for the transition period do not have a negative effect on the body and allow us to improve spermatogenesis indicators and increase testosterone levels.