Morinda citrifolia is a plant with broad nutraceutical and therapeutic effects and used in the traditional treatment of several ailments. The objective of this work is to investigate the phytochemistry of the fruit juice of M. citrifolia on one hand and on other hand to evaluate its antiradical and antibacterial activity. The phytochemical investigation was carried out by tube staining tests of the extract of two types of fruit juice of M. citrifolia . The antioxidant activity of these juices was evaluated by reducing the DPPH radical method. Concerning the antibacterial activity, it was tested on the in vitro growth of 10 reference bacterial strains using the well diffusion method. Qualitative phytochemistry of M. citrifolia fruit juices revealed the presence of large groups of secondary metabolites including polyphenols, reducing compounds, mucilage and terpernoids. The antioxidant activity of M. citrifolia fruit juices is dose-dependent and higher than that of ascorbic acid. Antimicrobial activity on other hand revealed that fruit juices inhibit growth inhibitory activity of Staphylococcus aureus , Pseudomonas aeruginosa , Proteus mirabilis , S. epidermidis , Proteus vulgaris , Streptococcus oralis , Enterococcus faecalis and Escherichia coli . This observed difference is significant for each juices on the strains ( p < 0.001). These results support the use of M. citrifolia in traditional medicine and are the starting points for the development of a new drug to combat both dietary conditions and chronic conditions associated with oxidative stress.
In order to evaluate the trophic behavior of Aedes aegypti in the city of Cotonou, southern Benin, a cross-sectional study was conducted in urban and periurban neighborhoods from April 2016 to August 2017 to collect Ae. Aegypti populations. To achieve this goal, day and night collections, twice a month for one year were done where Ae. Aegypti populations were caught by Human Landing Catch and BG-Sentinel traps. 3,892 Aedes caught by different methods showed that Ae. Aegypti and Ae. circumluteolus are more abundant in urban than peri-urban areas (p<0.05). The aggressive density of Ae. aegypti populations was significantly higher in urban areas (157.43 bites per man per hour) than in peri-urban areas (32.43 bites per man per hour) (p<0.05). Also, out of 250 females blood-fed Ae. Aegypti tested by ELISA (Enzyme Linked Immunosorbent Assay) technique for blood meal identification, 86.80% took their blood meal on humans compared to 4.4% which took their blood meal on sheeps. These findings showed that the city of Cotonou in southern Benin, offered good condition for the development of Ae. aegypti population. The anthropology and endophagy behavior of this mosquito observed through the results of this study is a very favorable clue to vector control strategies based on the use of long-lasting impregnated mosquito nets and insecticide residual sprays adopted in Benin.
RESUMEGardenia ternifolia est une plante à fleurs de la famille des Rubiaceae originaire des régions tropicales à subtropicalesd'Asie du Sud, d'Australasie et d'Océanie. Elle est très utilisée traditionnellement pour le traitement de diverses affections. Cette revue a pour objectif de faire une synthèse des études ethnobotanique, ethnopharmacologique, phytochimique, toxicologique de Gardenia ternifolia réalisées jusqu'en août 2018. Les informations scientifiques relatives à Gardenia ternifolia ont été recherchées sur plusieurs bases de données. Ainsi plusieurs publications scientifiques ont été explorées afin de rassembler un maximum de données fiables.Sur le plan de l'ethnopharmacologie les données collectées indiquent que Gardenia ternifolia est principalement utilisé dans le traitement du paludisme, l'hypertension, le diabète, la toux, l'asthme, le rhumatisme, la diarrhée, la carie dentaire, la lèpre, l'hernie, l'hémorroïde et le cancer. Les investigations phytochimiques réalisées sur les feuilles, les fruits et la racine de cette plante ont révélé la présence de saponine, des composés réducteurs, des stérols, des triterpènes et des substances polyphénoliques tels que les tanins, les flavonoïdes, les coumarines et les anthocyanes. Les tests toxicologiques, bien que rares, indiquent une innocuité des fruits et des racines de la plante. Gardenia ternifolia est une plante reconnue dans plusieurs pharmacopées africaines. Les études scientifiques déjà réalisées sur l'espèce évoquent une variété d'effets pharmacologiques tels que les effets antipaludiques, antioxydants, anticancéreux et antimicrobiens. Cependant des tests toxicologiques et pharmacologiques plus approfondis s'avèrent nécessaires en vue de relever tout le potentiel thérapeutique de cette plante. ABSTRACTGardenia ternifolia is a flowering plant of the family Rubiaceae from to the tropical to subtropical regions of South Asia, Australasia and Oceania. It is widely used traditionally for the treatment of various diseases. The purpose of this review is to summarize the ethnobotanical, ethnopharmacological, phytochemical E. AGBODJENTO et al. / Int. J. Biol. Chem. Sci. 12(6): 2922-2932, 2018 2923 and toxicological studies of Gardenia ternifolia carried out until August 2018. The scientific information related Gardenia ternifolia has been researched on several databases. Several scientific publications have been explored to gather as much reliable data as possible. In domain of ethnopharmacology the data collected show that Gardenia ternifolia is mainly used in the treatment of malaria, hypertension, diabetes, cough, asthma, rheumatism, diarrhea, tooth decay, leprosy, hernia, hemorrhoids and cancer. Phytochemical investigations carried out on the leaves, fruits and roots of this plant revealed the presence of saponins, reducing compounds, sterols, triterpenes and polyphenolic substances such as tannins, flavonoids, coumarins and anthocyanins. Toxicological testings, although rare, indicate a safety of fruits and roots of the plant. Gardenia ternifolia is a r...
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