Introduction: The authors propose a simple method for assessment of canine kidney size derived from the radiological technique described by Finco et al in 1971. Materials and methods: In 26 healthy dogs ultrasonography was used to measure the length, height, and thickness of each kidney. These measurements were correlated with the lengths of the fifth and sixth lumbar vertebrae (L5 and L6), also measured by ultrasound. The resulting values were compared with the linear correlation method and the ratios defined using descriptive statistics. Results: No significant differences were observed between the dimensions of the right and left kidneys. The length of both kidneys displayed significant correlation with both the length of L5 and that of L6. In both cases, the renal:vertebral length ratios ranged from 1.3 to 2.7. Discussion: The ratio of kidney length to the length of L5 or L6 can be considered a useful parameter for assessing the size of the kidneys in healthy dogs. The normal range we identified in this study (from 1.3 to 2.7) is sufficiently narrow to allow sonographic detection of even limited changes in renal length.Sommario Introduzione: Il nostro studio propone un metodo semplice di misurazione renale, che presenta un range di valori ridotto rispetto a quelli precedentemente proposti. Questo metodo si basa sulla valutazione del rapporto tra lunghezze renali e vertebrali. Materiali e metodi: Ventisei cani clinicamente sani sono stati sottoposti a esame ecografico. Sono state misurate le tre dimensioni di ciascun rene e la lunghezza della quinta (L5) e sesta vertebra lombare (L6). Attraverso la formula media (dimensione rene) AE 2 DS abbiamo determinato i range di riferimento del rapporto tra i parametri dimensionali del rene e la lunghezza di L5 e di L6. Risultati: Una correlazione lineare significativa è stata ottenuta solo per il rapporto tra la lunghezza del rene e la lunghezza di L5 e di L6. I nostri risultati hanno permesso di definire che il rapporto tra la lunghezza renale e la lunghezza dei corpi di L5 o di L6 è normalmente compreso tra i valori di 1,3 e 2,7. Discussione: Il rapporto tra la lunghezza renale e la lunghezza di L5 o di L6 può essere considerato un parametro utile per stimare le dimensioni renali del cane sano. Il range di normalità (da 1,3 a 2,7) risulta sufficientemente ristretto da suggerire che modificazioni anche limitate della lunghezza renale possano essere percepite ecograficamente. ª
Ultrasound has proven to be a useful tool in the evaluation of tenomusculoskeletal structures of shoulder in dogs with unremarkable radiographic findings. Our results suggest that ultrasonography is useful in the diagnosis of tendon abnormalities, fluid accumulation, muscle lacerations and bone surface irregularities as potential contributors to shoulder lameness in dogs.
Ductus venosus (DV) closure plays a key role in hepatic circulation adaptation to postnatal metabolic function, and DV patency might develop a congenital portosystemic shunt (CPSS). The noninvasive Color Flow Mapping (CFM) examination, a validated method to diagnose CPSS in adult dogs, is routinely performed to assess DV closure after birth in humans. This study aimed to describe the feasibility of the ultrasonographic evaluation of the DV after birth and to determine its closure time in healthy Great Dane neonates. Patency of DV in serial Color Flow Mapping (CFM) examinations and bodyweight (BW) were recorded on Days 0-3-6-9 in 24 neonates that were classified as having patent (PDV) or closed ductusvenosus (CDV) basing on CFM signal presence/absence. Since the 3rd day, DV diameter was recorded. Data were analysed by ANOVA (p < 0.05). All dogs resulted healthy 1 year later. The number of PDV and CDV puppies at birth was not different on Day 3 (24 and 0 vs. 22 and 2, PDV and CDV, respectively), whereas it resulted different on Days 6 (24 and 0 vs. 14 and 10) and 9 (24 and 0 vs. 0 and 24); on Day 3, it was different compared to Days 6 and 9; on Day 6, it was different from Day 9. Reduction of DV diameter resulted positively related to neonatal BW growth. The CFM evaluation of DV closure after birth in Great Dane puppies represents a feasible technique. Present results suggest the time of functional closure in normal neonates within 9 days after birth. Thus, CFM examination, as an early screening test for DV patency evaluation, performed 10 days after birth, may identify suspicious dogs at risk that would require further investigations. Further studies are needed to deepen the role of a delayed closure in low bodyweight and preterm puppies.
Background: Electrochemotherapy (ECT) combines the administration of anticancer drugs with the delivery of electric pulses, thus increasing the drug uptake through the cell membranes, resulting in increased efficacy. Aim: The aim of our study was to describe the tolerability and efficacy of ECT alone or in association with other treatment modalities for the management of apocrine gland anal sac adenocarcinoma (AGASAC). Methods: Medical records of dogs with a diagnosis of AGASAC that were treated with ECT alone or in combination with surgery/chemotherapy were retrospectively evaluated. Each dog received 20 mg/m2 of bleomycin intravenously. Based on the clinician’s decision, the primary tumor or tumor bed was also infiltrated with cisplatin at the dose of 0.5 mg/cm2. Trains of permeabilizing biphasic electric pulses were then applied under general anesthesia. Results: Ten dogs were enrolled in the study. Of those 10 dogs, only one received ECT for treatment of microscopic local disease, while in six cases ECT was the only treatment modality. In three dogs, ECT was followed by systemic medical treatment. Six dogs (60%) had a partial response (PR), three dogs (30%) had stable disease, and one dog treated for microscopic disease did not show any sign of local relapse for 305 days after treatment, being still alive and in complete remission at the time of writing this article. The median time to progression was 303 days and the median survival time was 365 days. The treatment was well tolerated and local side effects were minimal. No systemic effects were documented. Conclusion: This preliminary study suggests that ECT may be beneficial for dogs with AGASAC and could be a useful addition to the current therapeutic options in consideration of its low cost, limited toxicity, and ease of administration.
Recent literature has demonstrated that high-resolution ultrasonographic anatomy of the canine carpus is possible; however, only the structures of the dorsal face were described. The aims of this prospective study were: (1) to describe the normal ultrasonographic appearance of the carpal tendons in sporting Border Collies; (2) to measure the height, length, and thickness of the tendon at the radial ulnar notch level in order to create a baseline reference for the breed, and (3) to describe a standardised protocol to ultrasonographically evaluate the carpal faces and visible tendinous structures. A pilot study based on ten cadaveric front limbs was used to identify the structures. A subsequent clinical phase of the study using twenty-six Border Collies was recorded. The tendons of the Extensor Carpi Radialis, Extensor Digitorum Communis, andExtensor Digitorum Lateraliswere identified and followed from the tenomuscular junction to the distal insertion on the dorsal face of the digits. On the lateral face, the tendon of the Extensor Carpi Ulnaris was recognised and followed. On the palmar face, the two heads of the Flexor Carpi Ulnaris tendon ending on the accessory carpal bone, the adjacent Flexor Digitorum Superficialis tendon, and the deep and medially located Flexor Digitorum Profundus tendon were seen and followed. The Flexor Carpi Radialis and the Abductor Pollicis Longus tendons were seen in the medial carpal face. The ulnar notch of the radius was used as the measurement and starting point of the ultrasonography. These data could be used as a standard reference in the case of chronic overuse and trauma-induced changes in the canine carpus.
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