Objective To describe the obstetric outcomes of patients with multiple sclerosis (MS) and the impact of pregnancy and the postpartum period on the progression of the disease. Methods A case series study performed between December 2019 and February 2020, reporting pregnancies occurred between 1996 and 2019. The subjects included were women with MS undergoing follow-up at an MS referral center in Northeastern Brazil, and who had at least one pregnancy after the onset of MS symptoms, or who had their first relapse in the first year after delivery. Results In total, 26 women and 38 pregnancies were analyzed – 32 of them resulted in delivery, and the remaining 6, in miscarriages. There was a significant increase in the prevalence of relapse during the postpartum period when compared with the gestational period. In 16 (42.1%) of the pregnancies, there was exposure to disease-modifying therapies (DMTs) – 14 (36.8%), to interferon β, and 2 (5.3%), to fingolimod. Higher rates of abortion, prematurity and low birth weight were reported in the group was exposed to DMT when compared with the one who was not. Conclusion In the sample of the present study, there was a significant increase in the rate of MS relapse during the postpartum period when compared with the gestational period. Additionally, it seems that exposure to DMTs during pregnancy may affect the obstetric outcomes of the patients.

Existe um importante subfinanciamento do Sistema Único de Saúde e uma falta de informações acerca dos custos e demandas em saúde, dados fundamentais para gestores em saúde possam realizar as tomadas de decisão. Analisar as internações por AVC no SUS na região Nordeste, durante o período de 2008 a 2019. Trata-se de um estudo epidemiológico descritivo e retrospectivo, com posterior análise dos dados, realizado através do Sistema de Informações Hospitalares (SIH/SUS) do período de 2008 a 2019, no Nordeste. A maioria das internações ocorreu entre pessoas pardas (82,75%), da faixa etária dos 70-79 anos (26,93%). Observou-se um crescimento dos custos de internação, durante o período, em 251,62%, totalizando uma média anual de 37.750.782,1 reais. A taxa de letalidade no período foi de 17,38%, diminuindo 14,28%, relativamente, e o tempo de hospitalização aumentou 7,143%, alcançando, em 2019, 7,6 dias. O número de internações aumentou 124,2% no período, e em média, o custo por internação foi de 1050,65 reais. Os estados com maior porcentagem de mortalidade e custo por internação foi Sergipe e Alagoas. Dessa forma, compreendeu-se que houve um aumento do número de internações e do custo total nesse período. Além disso, houve um importante aumento do custo por internação. Ademais, apesar do aumento do número de óbitos por ano, houve uma redução da taxa de letalidade.

Introduction: Currently, there is an increase in the prevalence of chronic diseases, such as cancer. At the university, the acquisition of risky habits for this may be worrisome in the future. Thus, the assessment of the susceptibility of medical students can help to elucidate possible points of intervention, since it is a portion of the population oriented and supposedly encouraged to develop a healthy lifestyle. Objective: To evaluate the presence of risk factors associated with cancer in medical students at a public university in Paraíba. Patients and Methods: Cross-sectional and quantitative study was conducted with students from the first to the fourth year of the medical course at a public university. An objective questionnaire was used on the habits of sun and sexual exposure, dietary patterns, physical exercise, alcoholism, smoking, and others. The Chi-square test was used to assess the association between variables. The confidence interval and the level of significance considered were 95% and 5%, respectively. Results: A total of 211 students participated in the study. Of these, 35.5% reported using sunscreen. There was an association between the use of sunscreen and the female gender (p <0.05). The practice of physical exercise was similar between genders. Eating habits showed a preference for red meat and industrialized inputs. Alcoholism and smoking were reported by 62.6% and 31.3% of participants, respectively, associated with the male gender (p <0.05). Of those who reported sexual activity, 82.4% use condoms, most of them men. The presence of two or more risk factors was observed in 41.7% of the sample (p <0.05), with men being the majority. Conclusion: The male gender showed associations with the factor’s alcoholism, smoking and less use of sunscreen. The presence of two or more risk factors was observed in 41.7% of the participants.