Eighteen racemic 8.O.4'-neolignans with six different substitution patterns in rings A and B, in their ketone and in their erythro and threo alcoholic forms, were evaluated for antifungal activity by the agar dilution method. Only the alcohols exhibited a broad spectrum of activities against Microsporum canis, Microsporum gypseum, Tricophyton mentagrophytes, Tricophyton rubrum, and Epidermophyton floccosum. (+/-)-erythro-3,4-(methylenedioxy) -7-hydroxy-1'-allyl-3',5'-dimethoxy-8.O.4'-neolignan (11) was the most active compound in the series, and E. floccosum was the most susceptible species.

The kinetics of aggregation of para-casein micelles (pCM) and of heated para-casein micelles (HpCM) were studied and compared by estimating the initial rate of aggregation from the initial rate of turbidity increase. Aggregation of both pCM and HpCM suspensions appeared as cases of slow Brownian flocculation, with a steric contribution to the suspension's stability which could explain their aggregation behavior, including the presence of the Berridge effect at low temperatures. Glycerol addition to the medium, besides the reduction in aggregation rate by increase of medium viscosity, produced an initial aggregation rate increase, probably by interaction with the proteins of the micelle external layer. The differences observed between pCM and HpCM aggregation rate could be related to the changes introduced by high heating in the surface structure of the micelles. Keywords: Heated casein micelles; steric stabilization; rennet coagulation

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Teachers are a fundamental resource in the teaching-learning process and in many cases they represent important emotional role models for students. Nevertheless, occasionally their performance may diminish as a result of different psychosocial factors. Thus, teachers' psychological well being is imperative in the practice of the profession. The object of the present study was to determine the relation between burnout and psychological well-being in teachers of three different private establishments in Guatemala City, during 2019. The sample consisted of 68 individuals, both male and female, belonging to all school levels, ages 18 to 69. The study used a quantitative correlational approach, applying Maslach's Burnout Inventory and Ryffś Psychological Well Being Scale. The result was a negative correlation between these two variables, with magnitude of moderate association at 99 % (r = -.482, p < .001). Among the most important findings were the low levels of labor burnout, whereas the dimension of emotional exhaustion was high. Most teachers presented a high level in the general psychological well being index, with higher scores in environmental mastery and in life purpose, in contrast to self-acceptance, which showed low and medium levels.