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Technological advancement in wearable sensors (WS) and wearable biosensors (WBS) received much attention due to their ability to collect useful real-time information about the health of individuals and their high specificity, portability, data acquisition speed, low costs and low power consumption increasingly improved in the last

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Magnetic nanoparticles (MNP) have emerged as a relevant material for biomedical applications based on drug delivery systems and magnetic hyperthermia. When carefully tailored, their surface properties can enhance the solubility, bioavailability, permeability, metabolism, excretion, cell internalization and recognition of many medicines, which are parameters highly desired when one think in the development and efficiency increasing of several therapies. Allied to it, an interesting synergism can be achieved by the use of magnetic fields as trigger of drug release from thermosensitive polymer-modified MNP or as a tool to increase accumulation of medicine in specific site. Faced it, here it shows how surface engineering of MNP can improve its biomedical relevance due to enhancement of cellular recognition, biocompatibility and drug release of several medicines. Furthermore, particular attention will be paid to the use of magnetic hyperthermia, which has acted synergic to improve MNP effects of many drug delivery systems.

The use of lipases in industrials processes has increased due to its ability to catalyze total or partial hydrolysis reactions of fatty acids. However, due to the difficulty of isolation and purification of lipases, as well as its separation from the reaction medium, it becomes an expensive input. In this study, graphene oxide was used as carrier for enzymes. The magnetic properties of the carrier were obtained through decoration with magnetic iron oxide nanoparticles on graphene oxide surface.XRD was used to elucidate the structure and morphology of the compounds obtained. By measuring hydrolytic activity, it was possible to determine the optimum pH and temperature for three different types of immobilized lipases, being 37 °C and pH 8 (porcine pancreatic lipase), 50 °C and pH 6 (Candida rugosa lipase), and 40 °C and pH 9 (Aspergillus niger lipase). The enzymatic recovery test, during five minutes each, showed the immobilized porcine pancreatic lipase can be recycled six times without significant loss of catalytic activity. It was confirmed the efficiency of the magnetic graphene oxide as a carrier for different lipases allowing its use for transesterification process in mild temperature and pH conditions.