Development of direct late-stage installation of key fluorinated functional groups into aromatic systems is an important and challenging task of current organic chemistry. Herein, we report a novel palladium catalyzed trifluoroethylation process by C-H activation for the access of ortho trifluoroethylated aromatic ureas. The application of novel, highly active trifluoroethyl(mesityl)iodonium salt enables the efficient introduction of the trifluoroethyl group at 25 °C in 3 hours in high yields (up to 95%) with good functional group tolerance. Abstract: Development of direct late-stage installation of key fluorinated functional groups into aromatic systems is an important and challenging task of current organic chemistry. Herein, we report a novel palladium catalyzed
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