C-reactive protein (CRP) has been found to be ubiquitous in sera when determined by a highly sensitive method such as radioimmunoassay. Patients with some tumors appear to have much higher serum levels of CRP than others; in these, CRP seems to reflect the tumor burden. There is a positive correlation with TNM staging and the disease activity at the time of determination. CRP shows a high degree of ‘uniqueness’ when correlated with other routinely used cancer markers such as carcinoembryonic antigen, placental-like alkaline phosphatase and γ-glutamyltranspeptidase.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.