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The AOAC use-dilution test requires the replicate examination of a number of contaminated metal rings. Ten metal rings may be tested within the 20 min structure of the test. From a statistical and economical viewpoint, it would be highly desirable to increase the number of rings examined in a single test. A semiautomated ring carrier permits testing 200 rings within a 20 min test.

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No abstract

The historical application of probit analysis applied to the use-dilution disinfectant test is discussed. Attention is focused on earlier work which either deleted or incompletely applied confidence limits leading to much current controversy in disinfectant test interpretation. It is proposed that the probit analysis approach applied to disinfectants is indeed feasible and that a more complete application of confidence limits to the assay will yield more reliable data than those currently required for disinfectant product registration with the Environmental Protection Agency. A suggested modified registration protocol using probit analysis is offered as an alternative to the current registration guidelines.