There is a regional variation in conjunctival goblet cell distribution and density per unit of measurement. By secreting mucin goblet cells are involved in formation of tear film. Tear film instability is the basic sign of dry eye syndrome. Although dry eye syndrome can be a side effect of a disease, the most common cause is normal aging. The objective of the research was to determine goblet cell density in bulbar and lower forniceal conjunctiva and possible changes in goblet cell density related to age and sex. The research was conducted on 30 conjunctival samples of patients with no clinical changes of the conjunctiva. Tissue sections were stained with hematoxylin eosin (HE), periodic acid-schiff (PAS), alcian blue (AB)/PAS, Giemsa methods. Goblet cell density was 1.24 +/- 1.62 in bulbar conjunctiva and 30.21 +/- 14.32 in lower forniceal conjunctiva. Goblet cell distribution in the conjunctiva was unequal. A correlation between goblet cell density and age was not determined. Goblet cell density doesn't decrease with aging. No significant difference in goblet cell density between men and women was established.
Thyroglossal duct cysts have no specific cytological featres. Macrophages are the dominant cell population. Cholesterol crystals and stratified squamous epithelial cells enable differentiation of thyroglossal duct cysts from thyroid gland Cystic nodules. Fine-needle aspiration cytology is necessary when assessing the cellular composition of thyroglossal duct cysts in order to promptly detect the possible presence of malignant cells and to conduct a surgical treatment.
It can be concluded that the average value of thyroglobulin was significantly higher in patients with lymph node metastases in the neck. We are of the opinion that the determination of thyroglobulin, despite individual variations, may serve as a good indicator to assist in monitoring of patients surgically treated for differentiated thyroid cancer.
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