Intrathoracic extramedullary haematopoiesis (EMH) is a rare entity that is usually asymptomatic. A 44 year old man with alpha-thalassaemia is described who developed dyspnoea and massive left sided haemothorax. The haemoglobin disorder was established by Hgb H staining and haemoglobin electrophoretic studies. The DNA analysis revealed it to be a case of double heterozygous terminal codon mutation with the genotype CS / T . Computed tomographic scanning and magnetic resonance imaging of the thorax showed multiple paravertebral masses which were found by thoracoscopic biopsy to be extramedullary haematopoiesis. Although no additional sclerosing pleurodesis or low dose radiation therapy was given, the lung expanded well and there has been no recurrence of haemothorax to date.

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same patients, Kirby and associates 8 noted the frequency of blepharoconjunctivitis and meibomianitis and in 2 cases the later presence of cataracts. Kirby advanced the suggestion that the latter changes were also drug induced. These were unique changes, and it was the development of a similar series of reactions during the routine evaluation of a new antipsychotic compound which prompted this publication.WY-3457t is a butyrophenone and is not t Triparanol is 1-[p-(/l-diethylaminoethoxy ) phenyll-l-( p-tolyl ) -2-( p-chlorophenyl ) ethanol, and has the following structure:

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