A three-day-old newborn developed necrotizing enterocolitis in absence of the usual precipitating factors. Colonic perforation necessitated surgical intervention. After recovery cow's milk allergy was diagnosed. Probably this food allergy was the cause of the development of the necrotizing enterocolitis.
A case of total small bowel and colon aganglionosis is presented and 11 previous cases are briefly reviewed. The relatively long survival of our patient in an excellent condition provided the possibility of studying the behaviour of the aganglionic small bowel, disclosing that in the absence of propulsion, absorption is uninvolved and enteral feeding is possible. Aganglionosis of the ileum does not imply absence of muscle activity (leading to misleading bowel sounds and visible peristalsis on X-ray studies), and often the affected small bowel is dilated. In cases of Hirschsprung's disease with small bowel involvement we recommend as routine a full thickness biopsy of the jejunum, to ensure early diagnosis of the fatal disease of total intestinal aganglionosis.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.