The spontaneous hemoluminescence of blood and wound discharge in 26 patients operated in artificial circulation is studied. In uncomplicated course during artificial circulation and after operation independent of the effect of applied hemodilutants the increase of hemoluminescence of blood is found. Similar changes on days 23 after intervention are revealed in wound discharge. The indices approach to the initial values on days 45 after artificial circulation. Deviations from described dynamics coincide, as a rule, with grave postoperative state of patients. On the basis of the results of investigations the suggestions of the phagocytes activity changes in artificial circulation are made.
The results of treatment of 701 adult patients with congenital heart diseases from 1987 to 1997 are analyzed. As many as 248 operations with general postoperative lethality 3,2% are made. It is concluded on the necessity of improving the diagnosis of congenital heart diseases in children, especially in rural regions in relation to the high rate of inopportune revealing heart diseases resulting in the increase of the number of inoperable patients with pronounced pulmonary hypertension. The presence of symptoms or pronounced blood escape out of the left article into the right one in the absence of pulmonary hypertension is considered the indication to the radical correction of secondary defect of interatrial septum in adults. The radical heart disease correction in conditions of moderate hypotermy without artificial blood circulation is recommended in small secondary defect of interatrial septum
The need to study the indicators of humoral immunity in patients with extrahepatic cholestasis is dictated by the high frequency of purulent-septic complications observed in them [1, 8].
The frequency of involvement of the liver in the pathological process, accompanied by significant changes in the resistance of the body, and the unsatisfactory results of the treatment currently lead to an intensified search for new methods and means for the diagnosis and correction of lesions of the hepatoportal system in mechanical jaundice. The complex of changes developing in the liver with extrahepatic cholestasis and manifested in a combination of dystrophic, inflammatory, necrotic and sclerotic processes is well known. At the same time, in this type of pathology, in recent years, violations of immunological regulation have been increasingly noted, often underlying the development of structural and functional liver lesions [5, 6]. However, until now, in clinical practice, mainly biochemical blood tests with very relative reliability are used to assess the degree of involvement of the liver in the pathological process. In particular, we have previously shown that when comparing the functional and morphological indicators of the liver condition in patients with chronic calculous cholecystitis and its complications, a discrepancy between the data of biochemical blood tests and the severity of diffuse organ damage is found in 64%. There are no corresponding functional criteria for altered histophysiological parameters of the liver [2]. In this regard, a detailed comparative analysis of morphological, biochemical, immunological and clinical data obtained in pre and postoperative periods in patients with mechanical jaundice is theoretically and practically justified.
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