The anti‐inflammatory activities of different fractions of glycyrrhetinic acid or glycyrrhetic acid and some of its derivatives have been assessed in laboratory animals. Some, but not all, preparations have been found to be active using four established methods for testing anti‐inflammatory drugs. The findings provide a scientific basis for the clinical use of these compounds in inflammatory diseases, and may explain the discrepancies in the early clinical trials with this drug.
Thalidomide (a-phthalimidoglutarimide, " Distaval," " Contergan ") is a new sedative hypnotic drug which produces no toxic effects when administered orally to animals in massive doses. This lack of toxicity may be due to a limited absorption. The
Tall-and short-form Spartina alterniflora plants were transplanted from the Delaware marsh to common garden plots during the summer of 1978 and irrigated with saltwater three times a week during that and each subsequent growing season. Nine years later plant biomass, culm height, density, and diameter and flowering frequency remained distinct. Underground regrowth reserves and root profiles likewise remained distinct for the two forms. Since the two growth forms had been living in the same environment for 9 yr and had retained many morphological and physiological differences, some genetic control of the morphology and physiology of the two growth forms is highly probable.
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