A combined modeling and experimental strategy has been applied to the problem of stabilisation of a metastable conformational polymorph. For the first time additives have been successfully selected which by virtue of their conformation are able to selectively inhibit the appearance of the stable β polymorph of l-glutamic acid and hence stabilize the metastable α structure.

The crystal structure of y-quinacridone is reported and the relationship between the y-and y'-polymorphs discussed.

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