Die Umsetzung der Olefine (I) mit Formaldehyd (II) und den Nitrilen (III) in Gegenwart eines Säurekatalysators (Schwefelsäure, Chlorwasserstoff oder p‐Toluolsulfonsäure) liefert in Essigsäure bei 70‐100°C die 5,6‐Dihydro‐4H‐1,3‐oxazine (IV) (40 ‐ 58% Ausbeute).
By selective electrochemical oxidation at a nickel hydroxide electrode, benzyl chlorides, e.g. (I), are converted to the corresponding acids, e.g. (II).
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