The protective properties of recombinant Salmonella minnesota R595/pFS1 strain soon after immunization (1-3 days) are studied in a model of experimental mouse plague.Unlike the commercial EV strain Yersinia pestis vaccine produced at the Saratov AntiPlague Institute (Mikrob Research-Manufacturing Conglomerate), the experimental recombinant preparation affords a high level of protection from the 1st day postvaccination, and surpasses the commercial preparation in such parameters as LDs0 , mean survival time, and percentage of survivors. By the 21st day the protective indexes of both preparations are comparable.
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