Aims: The study was aimed at the Phytochemical and Proximate analysis of the flower, leaf, stem bark and seed of Mangifera indica for its ability to induce sedation. Place and Duration of Study: The fresh flower, leaf, stem bark and seed of Mangifera indica (Mango) were collected using secateurs and taken to the Department of Biological Sciences, Nigerian Defense Academy, Kaduna for specific identification and authentication by an expert. Methodology: The phytochemical analysis was carried out following the procedures described by Harbourne, (1998) while the methods of the Association of Official Analytical Chemists (AOAC, 2000) were used for the determination of moisture and ash content, crude fiber, lipids, proteins and carbohydrates and Nitrogen was determined using the micro Kjeldahl method described by (Gadelha et al., 2009). Results: A very significant percentage of protein, Flavonoid and terpenoids were detected in the plant samples especially Mangifera indica flower. Conclusion: A high presence of Flavonoid, Terpenoid and Protein in Mangifera indica plant parts is a sign of the possibility that the plant sample could contain a reasonable percentage of Apeginin, Myrcene and Tryptophan which are known active components to induce sedation and can feature in the future as a good source of sleep aid against insomnia.
Diarrhoea has been associated with significant morbidity and mortality, ranked the second cause of death in children aged 0 to 5 years. Bacteria, viruses, protozoa, and helminths have all been implicated in diarrhoea, however rotavirus and diarrhoeagenic E. coli (DEC) are the most common cause. This study aimed to determine the antibiotic susceptibility pattern of diarrheagenic Escherichia coli isolated from children 0-5 years attending selected hospitals in Kaduna metropolis. A total of 264 stool samples were collected from children attending four selected hospitals in Kaduna metropolis. Standard culture procedures and molecular techniques such as PCR and 16s rRNA were employed in isolation and characterization of diarrhoeagenic E. coli from the stool samples. The study established a prevalence of 24.2% for diarrheagenic Escherichia coli, and all the isolates demonstrated multiple antimicrobial resistance index (MARI) of 0.5 and above, and showed significant resistance against augmentin (100%), amoxacillin (100%), ampicillin-cloxacillin (ampiclox) (100%), erythromycin (100%), gentamycin (100%), cefoxitin (100%), cefuroxime (95%), ceftriazone (95%) and ceftaxidime (85%). The least (60%) resistance was observed against imipenem. The study concluded that antibiotics have not been very effective in the treatment of E. coli-related diarrhoea. The study, therefore, recommends the implementation of programmes geared towards good hygiene, good nutrition and good health
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.