Synthesis. -This method proceeds with high regioselectivity and gives access to substituted indole derivatives and therefore to the scaffolds of many natural products. The usefulness of this method was demonstrated by the syntheses of desoxyeseroline (XII) and esermethole (XIII).

Short and sweet: (−)‐Isatisine A was constructed using common and inexpensive building blocks, such as indole and D‐ribose (see scheme). The synthesis features an unprecedented intramolecular C glycosylation of an indole and an oxidative ring contraction.

To achieve sustainable development, the development and utilization of redox-active organic species in aqueous redox flow batteries provide broad prospects for large-scale and sustainable energy storage. Herein, we report a sulfonated ferrocene derivative, ferrocene ammonium sulfonate, that is stable and easy to synthesize. We applied it as a catholyte in zinc hybrid flow batteries. Through the adjustment of the electrolyte, the battery showed high capacity retention and efficiency. When the current density was 20 mA/cm2 and 0.5 M NaCl + 0.5 M NH4Cl solution was used as the supporting electrolyte, the capacity retention reached 92.55% after 100 consecutive charge/discharge cycles. In addition, the coulombic efficiency, energy efficiency, and voltage efficiency stayed at 98.33, 83.19, and 84.60%, respectively. This battery design puts forward an idea for developing low-cost materials and improving capacity retention.

An efficiently scalable synthesis of key intermediate toward mirabegron has been developed via a mixed anhydride method, employing PivCl instead of EDCI and HOBt. The developed process produced (R)-2-hydroxy-N-(4-nitrophenethyl)-2-phenylacetamide (10) in 91.5–92.3% yield and >99.0% HPLC purity under mild conditions. During this process, a side reaction induced by triethylamine hydrochloride was discovered and investigated, which was ultimately avoided by executing the reaction in a biphasic solvent system.

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