Several 3,5-dialkyl-4-hydroxybenzylidenemalononitriles and related compounds were tested for their fungicidal and acaricidal activities. The influence of structural variation on biological activity was studied by preparing and using a total of 22 compounds of benzyli denemalononitrile analogues. Amongst the compounds tested 3,5-di-tert-butyl and amyl-4-hydroxybenzylidenemalono nitrile were most effective against fungus, Piricularia oryzae Car. and mite, Tetranychus telarius L.
Seven optical active 2-benzylamino alcohols were synthesized by reduction of N-benzoyl derivatives of L-alanine, L-valine, L-leucine, L-phenylalanine, L-aspartic acid, L-glutamic acid and L-lysine and applied for the resolution of (•})-trans-chrysanthemic acid. d-trans-Chrys anthemic acid was obtained by resolution via the salts of 2-benzylamino alcohols derived from L-valine and L-leucine, while (-)-traps-chrysanthemic acid was prepared through the salts of the amino alcohols derived from L-alanine and L-phenylalanine.
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